Sex differences are important epidemiological factors that impact in the frequency and severity of infectious diseases. A clear sexual dimorphism in bacterial infections has been reported in both humans and an...
Authors: Edgar Ricardo Vázquez-Martínez, Elizabeth García-Gómez, Ignacio Camacho-Arroyo and Bertha González-Pedrajo
A dysbiosis in the intestinal microbiome plays a role in the pathogenesis of several immunological diseases. These diseases often show a sex bias, suggesting sex differences in immune responses and in the inte...
Authors: Marlies Elderman, Floor Hugenholtz, Clara Belzer, Mark Boekschoten, Adriaan van Beek, Bart de Haan, Huub Savelkoul, Paul de Vos and Marijke Faas
Doxorubicin (DOX), an anthracycline therapeutic, is widely used to treat a variety of cancer types and known to induce cardiomyopathy in a time and dose-dependent manner. Postmenopausal and hypertensive female...
Authors: Kaytee L. Pokrzywinski, Thomas G. Biel, Elliot T. Rosen, Julia L. Bonanno, Baikuntha Aryal, Francesca Mascia, Delaram Moshkelani, Steven Mog and V. Ashutosh Rao
This study aims to determine if there is sex bias in basic and preclinical research on age-related hearing loss for the 10-year period of 2006–2015, prior to the NIH mandate of including sex as a biological va...
Authors: Dillan F. Villavisanis, Katrina M. Schrode and Amanda M. Lauer
Cannabis is the most commonly used illicit drug. In the general population, its use has been linked to a heightened propensity for suicidal behavior (SB). We hypothesize that this association varies in patient...
Authors: Leen Naji, Tea Rosic, Brittany Dennis, Meha Bhatt, Nitika Sanger, Jackie Hudson, Natalia Mouravska, Lehana Thabane and Zainab Samaan
There is a complex interaction between female and male sex hormones and the risk of epilepsy. Whether prenatal exposure to higher levels of sex hormones affects the development of epilepsy in childhood or late...
Authors: Yanyan Mao, Linda Juel Ahrenfeldt, Kaare Christensen, Chunsen Wu, Jakob Christensen, Jørn Olsen and Yuelian Sun
Research into energy balance and growth has infrequently considered genetic sex, yet there is sexual dimorphism for growth across the animal kingdom. We test the hypothesis that in the chicken, there is a sex ...
Authors: S. D. Caughey, P. W. Wilson, N. Mukhtar, S. Brocklehurst, A. Reid, R. B. D’Eath, T. Boswell and I. C. Dunn
Differences in cardiovascular diseases are evident in men and women throughout life and are mainly attributed to the presence of sex hormones and chromosomes. Epigenetic mechanisms drive the regulation of the ...
Authors: Robin J. G. Hartman, Sarah E. Huisman and Hester M. den Ruijter
Sex differences in the incidence and prognosis of respiratory diseases have been reported. Studies have shown that women are at increased risk of adverse health outcomes from air pollution than men, but sex-sp...
Authors: Nathalie Fuentes, Arpan Roy, Vikas Mishra, Noe Cabello and Patricia Silveyra
Muscle fatigue induced by repetitive movements contributes to the development of musculoskeletal disorders. Men and women respond differently to muscle fatigue during isometric single-joint efforts, but sex di...
Authors: Jason Bouffard, Chen Yang, Mickael Begon and Julie Côté
Registry data worldwide indicate an overall female predominance for pulmonary arterial hypertension (PAH) of 2–4 over men. Genetic predisposition accounts for only 1–5% of PAH cases, while autoimmune diseases ...
Authors: Kyle A. Batton, Christopher O. Austin, Katelyn A. Bruno, Charles D. Burger, Brian P. Shapiro and DeLisa Fairweather
Sexual dimorphism in placental size and function has been described. Whether this influences the clinically important umbilical artery (UA) waveform remains controversial, although a few cross-sectional studie...
Authors: Christian Widnes, Kari Flo, Tom Wilsgaard, Torvid Kiserud and Ganesh Acharya
Over 100 mammalian G protein-coupled receptors are yet to be matched with endogenous ligands; these so-called orphans are prospective drug targets for the treatment of disease. GPR37L1 is one such orphan, abun...
Authors: James L. J. Coleman, Margaret A. Mouat, Jianxin Wu, Nikola Jancovski, Jaspreet K. Bassi, Andrea Y. Chan, David T. Humphreys, Nadine Mrad, Ze-Yan Yu, Tony Ngo, Siiri Iismaa, Cristobal G. dos Remedios, Michael P. Feneley, Andrew M. Allen, Robert M. Graham and Nicola J. Smith
Sexual parasites offer unique insights into the reproduction of unisexual and sexual populations. Because unisexuality is almost exclusively linked to the female sex, most studies addressed host-parasite dynam...
Authors: Marie Doležálková-Kaštánková, Nicolas B. M. Pruvost, Jörg Plötner, Heinz-Ulrich Reyer, Karel Janko and Lukáš Choleva
Noise-induced hearing loss (NIHL) is the most prevalent form of acquired hearing loss and affects about 40 million US adults. Among the suggested therapeutics tested in rodents, suberoylanilide hydroxamic acid...
Authors: Béatrice Milon, Sunayana Mitra, Yang Song, Zachary Margulies, Ryan Casserly, Virginia Drake, Jessica A. Mong, Didier A. Depireux and Ronna Hertzano
Differences in stroke care and health outcomes between men and women are debated. The objective of this study was to explore the relationship between patients’ sex and post-stroke health outcomes and received ...
Authors: Carl Willers, Ingrid Lekander, Elisabeth Ekstrand, Mikael Lilja, Hélène Pessah-Rasmussen, Katharina S. Sunnerhagen and Mia von Euler
Sexual dimorphism in DNA methylation levels is a recurrent epigenetic feature in different human cell types and has been implicated in predisposition to disease, such as psychiatric and autoimmune disorders. T...
Authors: Bianca Ho, Keelin Greenlaw, Abeer Al Tuwaijri, Sanny Moussette, Francisco Martínez, Elisa Giorgio, Alfredo Brusco, Giovanni Battista Ferrero, Natália D. Linhares, Eugênia R. Valadares, Marta Svartman, Vera M. Kalscheuer, Germán Rodríguez Criado, Catherine Laprise, Celia M. T. Greenwood and Anna K. Naumova
Incidence and prevalence of cardiovascular disease (CVD) differ between sexes, and women experience CVD later than men. Changes in fibrin clot lysability are associated with CVD, and the present study addresse...
Authors: Ramshanker Ramanathan, Niels Peter R. Sand, Johannes J. Sidelmann, Bjarne L. Nørgaard and Jørgen B. Gram
Disorders of sex development (DSD) have an estimated frequency of 0.5% of live births encompassing a variety of urogenital anomalies ranging from mild hypospadias to a discrepancy between sex chromosomes and e...
Authors: Hayk Barseghyan, Aleisha Symon, Mariam Zadikyan, Miguel Almalvez, Eva E. Segura, Ascia Eskin, Matthew S. Bramble, Valerie A. Arboleda, Ruth Baxter, Stanley F. Nelson, Emmanuèle C. Délot, Vincent Harley and Eric Vilain
Gut dysbiosis is observed in several neuropsychiatric disorders exhibiting increases in anxiety behavior, and recent work suggests links between gut inflammation and such disorders. One source of this inflamma...
Authors: Christopher T. Fields, Benoit Chassaing, Alexandra Castillo-Ruiz, Remus Osan, Andrew T. Gewirtz and Geert J. de Vries
Disruption of axonal transport plays a pivotal role in diabetic neuropathy. A sex-dimorphism exists in the incidence and symptomatology of diabetic neuropathy; however, no studies so far have addressed sex dif...
Authors: Marzia Pesaresi, Silvia Giatti, Roberto Spezzano, Simone Romano, Silvia Diviccaro, Tiziana Borsello, Nico Mitro, Donatella Caruso, Luis Miguel Garcia-Segura and Roberto Cosimo Melcangi
Unfortunately, after publication of this article [1], two errors were noticed. The names of Linnéa Karlsson Lind and Karin Schenck-Gustafsson were formatted incorrectly, attributing incorrect elements to the G...
Authors: Linnéa Karlsson Lind, Mia von Euler, Seher Korkmaz and Karin Schenck-Gustafsson
Citation:Biology of Sex Differences
2018
9:5
Published on: 18 January 2018
The
original article was published in Biology of Sex Differences
2017
8:32
Development of the placenta during the late first trimester is critical to ensure normal growth and development of the fetus. Developmental differences in this window such as sex-specific variation are implica...
Authors: Tania L. Gonzalez, Tianyanxin Sun, Alexander F. Koeppel, Bora Lee, Erica T. Wang, Charles R. Farber, Stephen S. Rich, Lauren W. Sundheimer, Rae A. Buttle, Yii-Der Ida Chen, Jerome I. Rotter, Stephen D. Turner, John Williams III, Mark O. Goodarzi and Margareta D. Pisarska
Global-local stimuli are hierarchical structures consisting of a larger global structure which is composed of smaller local stimuli. Numbers are also constructed hierarchically, with multi-digit numbers being ...
Authors: TiAnni Harris, Andrea Scheuringer and Belinda Pletzer
Chronic pain conditions are more prevalent in women, but most preclinical studies into mechanisms of pain generation are performed using male animals. Furthermore, whereas group III and IV nociceptive muscle a...
Authors: Jessica L. Ross, Luis F. Queme, Jordan E. Lamb, Kathryn J. Green and Michael P. Jankowski
