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Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia

In this article, which is part of the Hypertension, preeclampsia, renal and cardiovascular disease in pregnancy series, the authors postulate that senescence of mesenchymal stem cells (MSC), multipotent cells with pro-angiogenic activities, is one of the mechanisms by which systemic inflammation exerts inhibitory effects on angiogenesis in preeclampsia.

Aims and scope

Unlike any other scientific journal, Biology of Sex Differences focuses on sex differences in all aspects of an individual or organism: from molecules to behavior and from studies of cellular function to clinical research studies. This journal aims to improve understanding of basic biological principles mediating sex differences and foster development of therapeutic and diagnostic tools that are sex-specific. To the extent that gender influences biological outcomes, this journal also is interested in research addressing gender differences. Articles are expected to report results that directly compare sex/gender differences in the statistical analysis.

Biology of Sex Differences is the official journal of the Organization for the Study of Sex Differences, and a publication of the Society for Women's Health Research.



Articles

New special collection now publishing

Our special series on the topic of sex differences in obesity, insulin resistance, metabolic syndrome and the microbiome is now publishing. Read the collection of review and research articles here

Announcement

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

Submit a Topic

Do you have an idea for a thematic series? Submit your suggestion here. 

Editors

Editor-in-Chief
Jill BeckerUniversity of Michigan, USA

Associate Editors
Jeanette H. MagnusFaculty of Medicine, University of Oslo
Vera Regitz-ZagrosekCenter for Cardiovascular Research (CCR), Charité – Universitätsmedizin Berlin, Germany

Founding Editor
Arthur P Arnold, University of California, Los Angeles, USA

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Rhonda Voskuhl, M.D. President of the OSSD

Message from the OSSD President

Rhonda Voskuhl, M.D., President of OSSD

Rhonda Voskuhl M.D. is the current President of the OSSD. She holds the Jack H. Skirball Chair and is a Professor in the Department of Neurology and the Director of the Multiple Sclerosis Program at the David Geffen School of Medicine, University of California, Los Angeles (UCLA).

The Organization for the Study of Sex Differences (OSSD) is an international research society focused on the study of sex as a biologic variable in health and disease. Our members have tremendous expertise in a vast array of disciplines within science and medicine, linked by the common theme of the study of sex differences. Our annual meeting brings together these investigators to share mechanistic insights underlying sex differences to promote thinking outside the box of each specific discipline. OSSD also does advocacy and education regarding the importance of understanding sex differences that can translate into novel treatments optimally tailored for each sex for the benefit of both women and men. The Biology of Sex Differences is the official journal of the OSSD and a partner in this shared mission.

Affiliated with

  • Society for Women's Health Research

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