Skip to content


Aims and scope

Biology of Sex Differences considers manuscripts on all aspects of the effects of sex on biology and disease. Sex has profound effects on physiology and the susceptibility to disease. The function of cells and organs depends on their sex, determined by the interplay among the genome and biological and social environments. The study of sex differences is a discipline in itself, with its own concepts and methods that apply across tissues.

Biology of Sex Differences is the official journal of the Organization for the Study of Sex Differences, and a publication of the Society for Women's Health Research.


  1. Content type: Review


    Authors: Benjamin Abelson, Daniel Sun, Lauren Que, Rebecca A Nebel, Dylan Baker, Patrick Popiel, Cindy L Amundsen, Toby Chai, Clare Close, Michael DiSanto, Matthew O Fraser, Stephanie J Kielb, George Kuchel, Elizabeth R Mueller, Mary H Palmer, Candace Parker-Autry…

Most accessed articles RSS

View all articles

OSSD 2019 Meeting: May 5-8 in Washington, DC

New Content Item (1)

We hope everyone had a great #ossd2018 meeting in Atlanta and look forward to seeing you all again May 5-8, 2019 at the Washington Marriott Georgetown in Washington, DC.  This will be the 2nd international meeting of the OSSD with the International Gender Medicine Society.

Visit the OSSD website to learn more about the 2019 meeting.

Call for papers: Sex Differences in Obesity, Insulin Resistance, Metabolic Syndrome, and the Microbiome

Guest Editor: Kate Denton, Monash University

The Editors of Biology of Sex Differences extend an invitation to submit original research articles related to Sex Differences in Obesity, Insulin Resistance, Metabolic Syndrome, and the Microbiome:  

Submission Deadline: January, 2019.

Featured Articles

Sex differences in lower urinary tract biology and physiology

This review article provides insights into the biological differences between males and females at the cellular level, distinction which is often overlooked. In examining lower urinary tract bladder cells in males and females, the authors examine the impact of these sex-specific variations and identify important future directions for research in this area. Visit the blog from the Society for Women's Health Research to read more about the Interdisciplinary Network on Urological Health in Women research network that submitted the article.

Read the full review here

Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease

Using a mouse model, multi-omics, and big data, researchers at University of California-Los Angeles examined genetic and molecular pathways and their roles in the onset of non-alcoholic fatty liver disease (NAFLD) to reveal key sex differences in disease etiology and progression. Read more about how the authors harnessed big data to tackle the question of sex differences in NAFLD in their blog.

Read the full article here

Latest Tweets

BSD-OSSD annual award

Biology of Sex Differences, and the Organization for Study of Sex Differences have established an annual award to highlight the best research published in the journal by OSSD members.

The 2017 winner is Dr. Joanna Floros for the paper by George T. Noutsios, Nithyananda Thorenoor, Xuesheng Zhang, David S. Phelps, Todd M. Umstead, Faryal Durrani and Joanna Floros and titled: 
SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved 
Biology of Sex Differences 2017, 8:37 (4 December 2017)

Editor's profile

Jane ReckelhoffJane Reckelhoff, Editor-in-Chief

Dr. Reckelhoff is currently Professor and Chair of the Department of Cell and Molecular Biology and Director of the Women’s Health Research Center at the University of Mississippi Medical Center in Jackson. 

We are excited to have Dr Reckelhoff joining us as Editor-in Chief on the Biology of Sex Differences given her prominent position as a sex differences researcher and considerable editorial experience on journals such as Gender Medicine, Clinical Therapeutics, and the American Journal of Physiology, Regulatory, Integrative and Comparative Physiology.

Arthur P Arnold, Founding Editor

Arthur Arnold is a Distinguished Professor of Integrative Biology and Physiology, and Director of the Laboratory of Neuroendocrinology of the Brain Research Institute, at the University of California, Los Angeles.

 "Sex differences occur in many tissues and diseases. Biology of Sex Differences serves as a forum for discussion of the forces that make females and males different, and the downstream pathways that are affected by sex-specific forces. This information will be critical for discovery of factors, often more prevalent in one sex than the other, that alleviate disease."

Associate Editors' profiles

Photo of Barbara AlexanderBarbara T Alexander, Associate Editor

Dr. Barbara T. Alexander is a Professor of Physiology & Biophysics, at the University of Mississippi Medical Center in Jackson, MS.  Dr. Alexander serves at the Basic Science Director for the NIH/COBRE funded Mississippi Center of Excellence in Perinatal Research.


Photo of Kate DentonKate Denton, Associate Editor

Professor Kate Denton is a Principal Research Fellow of the National Health and Medical Research Council of Australia and Head, Cardiovascular Disease Program, Monash Biomedicine Discovery Institute, Monash University, Melbourne, Australia.


Photo of Vesna GarovicVesna Garovic, Associate Editor

Dr. Garovic is Professor of Medicine, Mayo Clinic Rochester, Minnesota, and holds joint appointments in Nephrology and Obstetrics and Gynecology. She currently serves as Chair for Research, Division of Nephrology and Hypertension, Mayo Clinic, and as Director, Clinical Research Office and Office of Clinical Trials, Department of Medicine, Mayo Clinic.

Photo of Radu IliescuRadu Iliescu, Associate Editor


Photo of Georgios KararigasGeorgios Kararigas, Associate Editor

G. Kararigas is a DZHK-Professor of Translational Gender Research with the Focus on Heart Failure at the Institute of Gender in Medicine of Charite University Hospital in Berlin. His primary research interests include mechanisms of sex differences in cardiovascular (patho)physiology, hormonal effects in the heart, gene expression and regulation.

Message from the OSSD President

Sabra Klein, OSSD PresidentSabra Klein, President of OSSD

Sabra Klein, PhD, is the current President of the Organization for the Study of Sex Differences, Associate Professor of Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public Health, and Co-Director of the Johns Hopkins Center for Women’s Health, Sex, and Gender Research.


‘The Organization for the Study of Sex Differences (OSSD) is the only scientific research society dedicated to the study of sex as a biological variable. Through our annual meeting and publications from our members, we seek to promote knowledge that sex impacts every cell, pathway, organ, and disease state in the body. As the biomedical sciences continue to appreciate that the progression, prognosis, pathogenesis, and outcome of diverse diseases differ between the sexes, OSSD and the Biology of Sex Differences are at the forefront, serving as experts in this scientific endeavor.’


Affiliated with

  • Society for Women's Health Research
  • Society for Women's Health Research

  • OSSD Logo new

2017 Journal Metrics