Aims and scope

Aims and scope

Biology of Sex Differences considers manuscripts on all aspects of the effects of sex on biology and disease.

Sex has profound effects on physiology and the susceptibility to disease. The function of cells and organs depends on their sex, determined by the interplay among the genome and biological and social environments. The study of sex differences is a discipline in itself, with its own concepts and methods that apply across tissues.

An understanding of the effect of sex on biology and disease requires an interdisciplinary approach in which the interaction of diverse sex-specific factors are studied at all levels, from molecular to the level of biological systems. The development of novel therapies for disease requires a sex-based conceptual framework.

Topical areas include, but are not limited to sex differences in:

  • the genome
  • epigenetics
  • molecular and cell biology
  • tissue biology
  • physiology
  • interaction of tissue systems, in any system including adipose, behavioral, cardiovascular, immune, muscular, neural, renal, and skeletal
  • clinical studies bearing on sex differences in disease or response to therapy

For further information about the material covered by Biology of Sex Differences, please see our "Submission Guidelines" below and to view details of our Editorial Board members, please visit theĀ  "Editorial Board" page.