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Fig. 1 | Biology of Sex Differences

Fig. 1

From: Gestational hypoxia in late pregnancy differentially programs subcortical brain maturation in male and female rat offspring

Fig. 1

Description of study design. For study one and two, Long–Evans pregnant female rats were exposed to chronic intermittent hypoxia (CIH) or room air (normoxia) on gestational days (GD) 15–19 (n = 6-8/group). For study one, dams were allowed to give birth (term = GD 22–23) and litters were reduced to eight pups/litter and, when possible, to equal number of males and females. Offspring were weaned at postnatal day (PND) 28 and separated into two groups: Puberty (n = 2/sex/dam; behavior testing = PND 40–45; euthanasia = PND 48) and Young Adult (n = 2/sex/dam; behavior testing = PND 60–65; euthanasia = PND 66). For study two, dams and fetuses were euthanized on GD 20

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Biology of Sex Differences

ISSN: 2042-6410

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