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Table 2 Examples of top ‘neurological disease’ functional categories that were significantly enriched in striatal testosterone-influenced genes

From: The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging

Function annotation p value Number of genes
Movement disorder 1.03E − 04 118
Congenital anomaly of brain 6.81E − 04 26
Dyskinesia 3.36E − 03 73
Huntington's disease 3.43E − 03 70
Hyperactive behavior 3.47E − 03 18
Schizophrenia 3.90E − 03 56
Jervell and Lange-Nielsen syndrome 4.66E − 03 2
Seizures 5.08E − 03 33
Mood disorder 5.35E − 03 50
Hydrocephalus 6.76E − 03 11
Ataxia 6.89E − 03 22
Amyotrophic lateral sclerosis 7.00E − 03 18
Incoordination 9.03E − 03 3
Oligodendroglioma 9.64E − 03 5
Spina bifida 1.33E − 02 7
Degeneration of brain 1.34E − 02 8
  1. Examples of top ‘neurological disease’ functional categories that were significantly enriched in the list of testosterone-influenced genes (XX vs. XX + T) in the striatum as determined by Ingenuity Pathway Analysis.