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Table 2 Examples of top ‘neurological disease’ functional categories that were significantly enriched in striatal testosterone-influenced genes

From: The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging

Function annotation

p value

Number of genes

Movement disorder

1.03E − 04

118

Congenital anomaly of brain

6.81E − 04

26

Dyskinesia

3.36E − 03

73

Huntington's disease

3.43E − 03

70

Hyperactive behavior

3.47E − 03

18

Schizophrenia

3.90E − 03

56

Jervell and Lange-Nielsen syndrome

4.66E − 03

2

Seizures

5.08E − 03

33

Mood disorder

5.35E − 03

50

Hydrocephalus

6.76E − 03

11

Ataxia

6.89E − 03

22

Amyotrophic lateral sclerosis

7.00E − 03

18

Incoordination

9.03E − 03

3

Oligodendroglioma

9.64E − 03

5

Spina bifida

1.33E − 02

7

Degeneration of brain

1.34E − 02

8

  1. Examples of top ‘neurological disease’ functional categories that were significantly enriched in the list of testosterone-influenced genes (XX vs. XX + T) in the striatum as determined by Ingenuity Pathway Analysis.