Intacts | Castrates | |||||
---|---|---|---|---|---|---|
Baseline CBF (mL/min) | 33.46 | ± | 5.10 | 35.63 | ± | 4.94 |
% Δ Flow | ||||||
T 1 nM | 5.31 | ± | 1.90 * | −0.84 | ± | 2.43 |
T 10 nM | 8.72 | ± | 2.90 *† | 2.57 | ± | 1.62 |
T 100 nM | 6.72 | ± | 2.65 * | 2.86 | ± | 1.16 * |
DHT 1 nM | 12.17 | ± | 5.62 *† | −1.64 | ± | 3.29 |
DHT 10 nM | 3.51 | ± | 1.45 * | 1.54 | ± | 2.14 |
DHT 100 nM | 6.94 | ± | 2.44 * | 2.08 | ± | 1.20 |
EpiT 1 nM | 7.85 | ± | 4.07 | 4.38 | ± | 2.63 |
EpiT 10 nM | 8.09 | ± | 3.71 * | 4.80 | ± | 2.44 |
EpiT 100 nM | 3.59 | ± | 1.78 | 2.60 | ± | 3.56 |
Baseline MAP (mmHg) | 64.93 | ± | 8.99 | 76.33 | ± | 8.85 |
% Δ Pressure | ||||||
T 1 nM | −0.13 | ± | 0.47 | −0.23 | ± | 0.38 |
T 10 nM | −0.51 | ± | 0.38 | −1.92 | ± | 0.53 * |
T 100 nM | −0.4 | ± | 0.51 | −1.64 | ± | 0.49 * |
DHT 1 nM | −0.78 | ± | 0.52 | −0.71 | ± | 0.63 |
DHT 10 nM | −0.7 | ± | 0.32 | −1.12 | ± | 0.74 |
DHT 100 nM | −0.33 | ± | 0.26 | −0.63 | ± | 0.42 |
EpiT 1 nM | −0.37 | ± | 0.53 | −0.95 | ± | 0.52 |
EpiT 10 nM | −0.38 | ± | 0.33 | −0.63 | ± | 0.33 |
EpiT 100 nM | −0.64 | ± | 0.40 | −0.93 | ± | 0.42 * |