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  1. Hypertension remains the leading risk factor for cardiovascular disease. Young females tend to be protected from hypertension compared with age-matched males. Although it has become increasingly clear that the...

    Authors: Elizabeth C. Snyder, Mahmoud Abdelbary, Ahmed El-Marakby and Jennifer C. Sullivan
    Citation: Biology of Sex Differences 2022 13:17
    Content type: Research Published on:

  2. Prior research indicates that at least 35% of Alzheimer’s disease and related dementia risk may be amenable to prevention. Subjective cognitive decline is often the first indication of preclinical dementia, wi...

    Authors: Karen C. Schliep, William A. Barbeau, Kristine E. Lynch, Michelle K. Sorweid, Michael W. Varner, Norman L. Foster and Fares Qeadan
    Citation: Biology of Sex Differences 2022 13:16
    Content type: Research Published on:

  3. Sex-based differences are crucial to consider in the formulation of a personalized treatment plan. We evaluated sex-based differences in adherence and remotely monitored biometric, psychometric, and biomarker ...

    Authors: Lili Barsky, William Speier, Garth Fuller, Susan Cheng, Andy Kim, Sandy Joung, Corey Arnold, Shivani Dhawan, Mayra Lopez, Mitra Mastali, Irene van den Broek, Janet Wei, Brennan Spiegel, Jennifer E. Van Eyk, C. Noel Bairey Merz and Chrisandra Shufelt
    Citation: Biology of Sex Differences 2022 13:15
    Content type: Research Published on:

  5. Sex differences are essential factors in disease etiology and manifestation in many diseases such as cardiovascular disease, cancer, and neurodegeneration [33]. The biological influence of sex differences (includ...

    Authors: Jennifer L. Fisher, Emma F. Jones, Victoria L. Flanary, Avery S. Williams, Elizabeth J. Ramsey and Brittany N. Lasseigne
    Citation: Biology of Sex Differences 2022 13:13
    Content type: Review Published on:

  6. Women and men are suggested to have differences in vulnerability to neuropsychiatric disorders, including major depressive disorder (MDD), generalized anxiety disorder (GAD), schizophrenia, eating disorders, i...

    Authors: Parnian Shobeiri, Amirali Kalantari, Antônio L. Teixeira and Nima Rezaei
    Citation: Biology of Sex Differences 2022 13:12
    Content type: Review Published on:

  8. We assessed the sex differences in the association between blood pressure categories and glucose intolerance status with overall and ischemic stroke among Iranian adults.

    Authors: Azra Ramezankhani, Donna Parizadeh, Fereidoun Azizi and Farzad Hadaegh
    Citation: Biology of Sex Differences 2022 13:10
    Content type: Research Published on:

  9. Neurogenesis in the hippocampus endures across the lifespan but is particularly prolific during the first postnatal week in the developing rodent brain. The majority of new born neurons are in the dentate gyru...

    Authors: S. L. Stockman, K. E. Kight, J. M. Bowers and M. M. McCarthy
    Citation: Biology of Sex Differences 2022 13:9
    Content type: Research Published on:

  10. Beyond the degree of adiposity, the pattern of fat distribution has a profound influence on cardiometabolic risk. It is unclear if sex differences in body fat distribution can potentially explain any sex diffe...

    Authors: Christina Strack, Gundula Behrens, Sabine Sag, Margareta Mohr, Judith Zeller, Claas Lahmann, Ute Hubauer, Thomas Loew, Lars Maier, Marcus Fischer and Andrea Baessler
    Citation: Biology of Sex Differences 2022 13:8
    Content type: Research Published on:

  11. Although biological males and females are equally likely to become infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), evidence has mounted that males experience higher severity and fat...

    Authors: Cosby G. Arnold, Anne Libby, Alexis Vest, Andrew Hopkinson and Andrew A. Monte
    Citation: Biology of Sex Differences 2022 13:7
    Content type: Review Published on:

  12. Birds exhibit a unique asymmetry in terms of gonad development. The female left gonad generates a functional ovary, whereas the right gonad regresses. In males, both left and right gonads would develop into te...

    Authors: Yunqi Jiang, Zhelun Peng, Qiu Man, Sheng Wang, Xiaochen Huang, Lu Meng, Heng Wang and Guiyu Zhu
    Citation: Biology of Sex Differences 2022 13:6
    Content type: Research Published on:

  13. Metabolic syndrome (MetS) refers to a cluster of co-existing cardio-metabolic risk factors, including visceral obesity, dyslipidemia, hyperglycemia with insulin resistance, and hypertension. As there is a clos...

    Authors: Melinda E. Tóth, Márta Sárközy, Gergő Szűcs, Brigitta Dukay, Petra Hajdu, Ágnes Zvara, László G. Puskás, Gábor J. Szebeni, Zsófia Ruppert, Csaba Csonka, Ferenc Kovács, András Kriston, Péter Horváth, Bence Kővári, Gábor Cserni, Tamás Csont…
    Citation: Biology of Sex Differences 2022 13:5
    Content type: Research Published on:

  14. Biological processes involving environmental and genetic factors drive the interplay between age- and sex-regulating lipid profile. The relation between variations in the LPA gene with increasing the risk of coro...

    Authors: Hossein Lanjanian, Leila Najd Hassan Bonab, Mahdi Akbarzadeh, Maryam Moazzam-Jazi, Asiyeh Sadat Zahedi, Sajedeh Masjoudi and Maryam S. Daneshpour
    Citation: Biology of Sex Differences 2022 13:4
    Content type: Research Published on:

  15. There are sex differences in addiction behaviors. To develop a pre-clinical animal model to investigate this, the present study examined sex differences in sucrose taking and seeking using Long-Evans rats.

    Authors: Jeffrey W. Grimm, Katherine North, Madeleine Hopkins, Kyle Jiganti, Alex McCoy, Josef Šulc, Derek MacDougall and Frances Sauter
    Citation: Biology of Sex Differences 2022 13:3
    Content type: Research Published on:

  16. Focused evaluations on potential sex differences in the angiographic findings of the coronary arteries are scarce. This study was performed to compare the angiographic extent and localization of coronary steno...

    Authors: Hack-Lyoung Kim, Hyun-Jin Kim, Mina Kim, Sang Min Park, Hyun Ju Yoon, Young Sup Byun, Seong Mi Park, Mi Seung Shin, Kyung-Soon Hong and Myung-A Kim
    Citation: Biology of Sex Differences 2022 13:2
    Content type: Research Published on:

  18. Sex differences in COVID-19 are increasingly recognized globally. Although infection rates are similar between the sexes, men have more severe illness. The mechanism underlying these sex differences is unknown...

    Authors: Shaohua Qi, Conelius Ngwa, Diego A. Morales Scheihing, Abdullah Al Mamun, Hilda W. Ahnstedt, Carson E. Finger, Gabriela Delevati Colpo, Romana Sharmeen, Youngran Kim, HuiMahn A. Choi, Louise D. McCullough and Fudong Liu
    Citation: Biology of Sex Differences 2021 12:66
    Content type: Research Published on:

  19. Body height is a marker of childhood health and cumulative net nutrition during growth periods. However, sex-specific associations between body height and cognitive impairment are not well known in northern ru...

    Authors: Dongwang Qi, Chanhong Shi, Rongyan Mao, Xuewei Yang, Jinhui Song, Yanjia Wang, Jun Tu, Jinghua Wang, Xianjia Ning and Yi Wu
    Citation: Biology of Sex Differences 2021 12:65
    Content type: Research Published on:

  20. Lung adenocarcinoma (LUAD) is one of the most important subtypes of lung cancer. Compared with male LUAD patients, female patients have a higher incidence, but better long-term survival rate, with unknown reas...

    Authors: Tao Fan, Chunxiang Li and Jie He
    Citation: Biology of Sex Differences 2021 12:64
    Content type: Research Published on:

  21. Several biomarkers have been identified to predict the outcome of COVID-19 severity, but few data are available regarding sex differences in their predictive role. Aim of this study was to identify sex-specifi...

    Authors: Maria Teresa Pagano, Daniela Peruzzu, Luca Busani, Marina Pierdominici, Anna Ruggieri, Andrea Antinori, Gianpiero D’Offizi, Nicola Petrosillo, Fabrizio Palmieri, Pierluca Piselli, Stefania Cicalini, Stefania Notari, Emanuele Nicastri, Chiara Agrati, Giuseppe Ippolito, Francesco Vaia…
    Citation: Biology of Sex Differences 2021 12:63
    Content type: Research Published on:

  22. Despite growing recognition of the importance of sex and gender considerations in health research, they are rarely integrated into research design and reporting. We sought to assess the integration of sex, as ...

    Authors: Amédé Gogovor, Hervé Tchala Vignon Zomahoun, Giraud Ekanmian, Évèhouénou Lionel Adisso, Alèxe Deom Tardif, Lobna Khadhraoui, Nathalie Rheault, David Moher and France Légaré
    Citation: Biology of Sex Differences 2021 12:62
    Content type: Review Published on:

  23. Current methods fail to accurately predict women at greatest risk of developing fetal growth restriction (FGR) or related adverse outcomes, including stillbirth. Sexual dimorphism in these adverse pregnancy ou...

    Authors: Bernadette C. Baker, Sylvia Lui, Isabel Lorne, Alexander E. P. Heazell, Karen Forbes and Rebecca L. Jones
    Citation: Biology of Sex Differences 2021 12:61
    Content type: Research Published on:

  24. Several chronic pain disorders, such as migraine and fibromyalgia, have an increased prevalence in the female population. The underlying mechanisms of this sex-biased prevalence have yet to be thoroughly docum...

    Authors: Aidan Levine, Erika Liktor-Busa, Austin A. Lipinski, Sarah Couture, Shreya Balasubramanian, Sue A. Aicher, Paul R. Langlais, Todd W. Vanderah and Tally M. Largent-Milnes
    Citation: Biology of Sex Differences 2021 12:60
    Content type: Research Published on:

  25. There is good evidence that female infants are particularly vulnerable to poor emotional outcomes following in utero glucocorticoid exposure. It is currently unclear whether such effects might persist into the...

    Authors: Elizabeth C. Braithwaite, Helen Sharp, Andrew Pickles, Jonathan Hill and Nicola Wright
    Citation: Biology of Sex Differences 2021 12:59
    Content type: Research Published on:

  26. Women with preeclampsia (PE) have a greater risk of developing hypertension, cardiovascular disease (CVD), and renal disease later in life. Angiotensin II type I receptor agonistic autoantibodies (AT1-AAs) are...

    Authors: George W. Booz, Daniel Kennedy, Michael Bowling, Taprieka Robinson, Daniel Azubuike, Brandon Fisher, Karen Brooks, Pooja Chinthakuntla, Ngoc H. Hoang, Jonathan P. Hosler and Mark W. Cunningham Jr.
    Citation: Biology of Sex Differences 2021 12:58
    Content type: Research Published on:

  27. In the United States, women are at a higher risk of developing vision impairment or a serious eye disease (such as age-related macular degeneration, thyroid eye disease, or chronic dry eye disease) than men. D...

    Authors: Irene O. Aninye, Kathleen Digre, M. Elizabeth Hartnett, Kira Baldonado, Erin M. Shriver, Laura M. Periman, Julie Grutzmacher and Janine A. Clayton
    Citation: Biology of Sex Differences 2021 12:57
    Content type: Review Published on:

  28. Hair cortisol concentration (HCC) has received attention as a useful marker of stress, but evidence on associations between psychological factors and cortisol concentration is inconsistent. The purpose of this...

    Authors: Won Jae Kim, Kyung Mee Park, Jung Tak Park, Eunchong Seo, Suk Kyoon An, Hye Yoon Park and Eun Lee
    Citation: Biology of Sex Differences 2021 12:56
    Content type: Research Published on:

  29. Sex differences in the rates of affective disorders have been recognized for decades. Studies of physiologic sex-related differences in animals and humans, however, have generally yielded little in terms of ex...

    Authors: Christopher Sikes-Keilp and David R. Rubinow
    Citation: Biology of Sex Differences 2021 12:55
    Content type: Review Published on:

  30. Stroke disproportionately affects men and women, with women over 65 years experiencing increased severity of impairment and higher mortality rates than men. Human studies have explored risk factors that contri...

    Authors: Karen R. Bottenfield, Bethany G. E. Bowley, Monica A. Pessina, Maria Medalla, Douglas L. Rosene and Tara L. Moore
    Citation: Biology of Sex Differences 2021 12:54
    Content type: Research Published on:

  32. The AMP-activated protein kinase (AMPK) is a major regulator of cellular energetics which plays key role in acute metabolic response and in long-term adaptation to stress. Recent works have also suggested non-...

    Authors: Lucile Grimbert, Maria-Nieves Sanz, Mélanie Gressette, Catherine Rucker-Martin, Marta Novotova, Audrey Solgadi, Ahmed Karoui, Susana Gomez, Kaveen Bedouet, Eric Jacquet, Christophe Lemaire, Vladimir Veksler, Mathias Mericskay, Renée Ventura-Clapier, Jérôme Piquereau and Anne Garnier
    Citation: Biology of Sex Differences 2021 12:52
    Content type: Research Published on:

  33. Incentives to promote drinking (“happy hour”) can encourage faster rates of alcohol consumption, especially in women. Sex differences in drinking dynamics may underlie differential health vulnerabilities relat...

    Authors: Annabelle Flores-Bonilla, Barbara De Oliveira, Andrea Silva-Gotay, Kyle W. Lucier and Heather N. Richardson
    Citation: Biology of Sex Differences 2021 12:51
    Content type: Research Published on:

  34. Sex differences are underappreciated in the current understanding of cardiovascular disease (CVD) in association with chronic kidney disease (CKD). A hallmark of CKD is vascular aging that is characterised, am...

    Authors: Agne Laucyte-Cibulskiene, Liam J. Ward, Thomas Ebert, Giulia Tosti, Claudia Tucci, Leah Hernandez, Alexandra Kautzky-Willer, Maria-Trinidad Herrero, Colleen M. Norris, Louise Pilote, Magnus Söderberg, Torkel B. Brismar, Jonaz Ripsweden, Peter Stenvinkel, Valeria Raparelli and Karolina Kublickiene
    Citation: Biology of Sex Differences 2021 12:50
    Content type: Research Published on:

  35. Uremic cardiomyopathy is a common cardiovascular complication of chronic kidney disease (CKD) characterized by left ventricular hypertrophy (LVH) and fibrosis enhancing the susceptibility of the heart to acute...

    Authors: Márta Sárközy, Fanni Magdolna Márványkövi, Gergő Szűcs, Zsuzsanna Z. A. Kovács, Márton R. Szabó, Renáta Gáspár, Andrea Siska, Bence Kővári, Gábor Cserni, Imre Földesi and Tamás Csont
    Citation: Biology of Sex Differences 2021 12:49
    Content type: Research Published on:

  36. Authors: Virginia Quaresima, Cristina Scarpazza, Alessandra Sottini, Chiara Fiorini, Simona Signorini, Ottavia Maria Delmonte, Liana Signorini, Eugenia Quiros-Roldan and Luisa Imberti
    Citation: Biology of Sex Differences 2021 12:48
    Content type: Correction Published on:

    The original article was published in Biology of Sex Differences 2021 12:45

  37. Context-dependent execution or inhibition of a response is an important aspect of executive control, which is impaired in neuropsychological and addiction disorders. Transcranial direct current stimulation (tD...

    Authors: Daniel J. Fehring, Ranshikha Samandra, Zakia Z. Haque, Shapour Jaberzadeh, Marcello Rosa and Farshad A. Mansouri
    Citation: Biology of Sex Differences 2021 12:47
    Content type: Research Published on:

  38. Estradiol potentiates drug-taking behaviors, including motivation to self-administer cocaine and reinstatement of drug-seeking after extinction in females, but not males. The dorsolateral stratum (DLS) is a re...

    Authors: Jacqueline A. Quigley, Molly K. Logsdon, Brianna C. Graham, Kendra G. Beaudoin and Jill B. Becker
    Citation: Biology of Sex Differences 2021 12:46
    Content type: Research Published on:

  39. Coronavirus disease 2019 (COVID-19) severity seems to be influenced by genetic background, sex, age, and presence of specific comorbidities. So far, little attention has been paid to sex-specific variations of...

    Authors: Virginia Quaresima, Cristina Scarpazza, Alessandra Sottini, Chiara Fiorini, Simona Signorini, Ottavia Maria Delmonte, Liana Signorini, Eugenia Quiros-Roldan and Luisa Imberti
    Citation: Biology of Sex Differences 2021 12:45
    Content type: Research Published on:

    The Correction to this article has been published in Biology of Sex Differences 2021 12:48

  40. The menopause transition is associated with an increased risk of depression. While the mechanisms behind this increased risk are not well understood, the changing perimenopausal hormonal environment has been h...

    Authors: Bethany Sander, Amira Muftah, Laurie Sykes Tottenham, Julia A. Grummisch and Jennifer L. Gordon
    Citation: Biology of Sex Differences 2021 12:44
    Content type: Research Published on:

  41. Sexual dimorphism in the immune system is evidenced by a higher prevalence of autoimmune diseases in women and higher susceptibility to infectious diseases in men. However, the molecular basis of these sex-bas...

    Authors: Jisun So, Albert K. Tai, Alice H. Lichtenstein, Dayong Wu and Stefania Lamon-Fava
    Citation: Biology of Sex Differences 2021 12:43
    Content type: Research Published on:

  42. Authors: Marianna Török, Petra Merkely, Anna Monori-Kiss, Eszter Mária Horváth, Réka Eszter Sziva, Borbála Péterffy, Attila Jósvai, Alex Ali Sayour, Attila Oláh, Tamás Radovits, Béla Merkely, Nándor Ács, György László Nádasy and Szabolcs Várbíró
    Citation: Biology of Sex Differences 2021 12:42
    Content type: Correction Published on:

    The original article was published in Biology of Sex Differences 2021 12:37

  43. Women attempt to quit smoking less often than men and are less likely to maintain abstinence. Reproductive hormones have been postulated as a reason for this sex difference, though this remains to be clarified...

    Authors: Ashley R. Ethier, Ty L. McKinney, Laurie Sykes Tottenham and Jennifer L. Gordon
    Citation: Biology of Sex Differences 2021 12:41
    Content type: Research Published on:

  44. Urolithiasis is considered a vital public health issue with a substantial burden on kidney function. Additionally, only few reports focused on the gender difference in patients with urolithiasis. Therefore, th...

    Authors: Tsu-Ming Chien, Yen-Man Lu, Ching-Chia Li, Wen-Jeng Wu, Hsueh-Wei Chang and Yii-Her Chou
    Citation: Biology of Sex Differences 2021 12:40
    Content type: Research Published on:

  45. To date, there is no clearly defined association between plasma selenium levels and first stroke. We aimed to investigate the association between baseline plasma selenium and first stroke risk in a community-b...

    Authors: Huan Hu, Chonglei Bi, Tengfei Lin, Lishun Liu, Yun Song, Binyan Wang, Ping Wang, Ziyi Zhou, Chongqian Fang, Hai Ma, Xiao Huang, Lihua Hu, Xiping Xu, Hao Zhang, Yong Huo, Xiaobin Wang…
    Citation: Biology of Sex Differences 2021 12:39
    Content type: Research Published on:

  46. Human placental DNA methylation (DNAme) data is a valuable resource for studying sex differences during gestation, as DNAme profiles after delivery reflect the cumulative effects of gene expression patterns an...

    Authors: Amy M. Inkster, Victor Yuan, Chaini Konwar, Allison M. Matthews, Carolyn J. Brown and Wendy P. Robinson
    Citation: Biology of Sex Differences 2021 12:38
    Content type: Research Published on:

  47. We aimed to identify sex differences in the network properties and to recognize the geometric alteration effects of long-term swim training in a rat model of exercise-induced left ventricular (LV) hypertrophy.

    Authors: Marianna Török, Petra Merkely, Anna Monori-Kiss, Eszter Mária Horváth, Réka Eszter Sziva, Borbála Péterffy, Attila Jósvai, Alex Ali Sayour, Attila Oláh, Tamás Radovits, Béla Merkely, Nándor Ács, György László Nádasy and Szabolcs Várbíró
    Citation: Biology of Sex Differences 2021 12:37
    Content type: Research Published on:

    The Correction to this article has been published in Biology of Sex Differences 2021 12:42

  48. Vancomycin-resistant enterococci (VRE) have emerged in the healthcare setting worldwide. Infections with these pathogens, i.e., bloodstream infections (BSI), are accompanied with an impaired patient outcome. D...

    Authors: Carlos L. Correa-Martínez, Franziska Schuler and Stefanie Kampmeier
    Citation: Biology of Sex Differences 2021 12:36
    Content type: Review Published on:

  50. Adverse drug events, including adverse drug reactions (ADRs), are responsible for approximately 5% of unplanned hospital admissions: a major health concern. Women are 1.5–1.7 times more likely to develop ADRs....

    Authors: L. C. Hendriksen, P. D. van der Linden, A. L. M. Lagro-Janssen, P. M. L. A. van den Bemt, S. J. Siiskonen, M. Teichert, J. G. Kuiper, R. M. C. Herings, B. H. Stricker and L. E. Visser
    Citation: Biology of Sex Differences 2021 12:34
    Content type: Research Published on:
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Biology of Sex Differences

ISSN: 2042-6410

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