Fig. 8

Compulsive behaviors. CIH increased marble burying in vehicle male rats, but not in vehicle females. MT prevented CIH from increasing marbles buried in males. In MT females, CIH decreased marble burying, with no effect in MT males. MT increased marble burying in normoxic females, but not in normoxic males. Raw values are shown and error bars denote mean ± S.E.M. Analyzed by 3-way ANOVA with Fisher’s LSD multiple comparisons tests. ANOVA significance indicated by: **p ≤ 0.01; Post-hoc significance indicated by unique letters (p ≤ 0.05). Significant effects observed: CIH X Sex (F_{1, 64} = 6.499; p = 0.013; η² = 0.075); CIH X MT (F_{1, 64} = 5.669; p = 0.020; η² = 0.065); MT X Sex (F_{1, 64} = 4.437; p = 0.039; η² = 0.051). CIH chronic intermittent hypoxia, MT MitoTEMPOL