Fig. 1

Auxological parameters of body and bone (femur and tibia) length in Pappa2^ko/ko and Pappa2^wt/wt mice (males and females) at weaning (A), puberty (B) and adulthood (C-G). Data are represented as mean ± S.E.M (N = 8–10 per experimental group). Two-way ANOVA and Tukey-corrected tests: ***p < 0.001 versus respective wt/wt males and females; ^#/##/###p < 0.05/0.01/0.001 versus respective wt/wt and ko/ko males