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Fig. 3 | Biology of Sex Differences

Fig. 3

From: Reprograming skin fibroblasts into Sertoli cells: a patient-specific tool to understand effects of genetic variants on gonadal development

Fig. 3

46, XY DSD and 46,XX fibroblast derived SLCs exhibit varying degrees of change in morphology after 1 month trans-differentiation. Representative images of GFPC and 6TF SLCs on Day7 and Day28; Shape factor quantifications (N = 3, n = 50–60 for each group). *Represent p values calculated from Mann Whitney statistical tests conducted between the indicated groups for (A) 46, XY; SRXY1 (B) 46,XY; CD; (C) 46,XY; WT1 and (D) 46,XX (E) Shape factor quantifications comparing GFPC and 6TF SLC among all the four genetic backgrounds

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