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Fig. 5 | Biology of Sex Differences

Fig. 5

From: Sex disparities revealed by single-cell and bulk sequencing and their impacts on the efficacy of immunotherapy in esophageal cancer

Fig. 5

Development and validation of a novel sex-related signature (SRS) to predict the efficacy of immunotherapy. (A and D) Kaplan-Meier survival analysis in subgroups stratified by SRS (A) or TMB (D) in the training cohort with 60 EC patients. (B and E) Kaplan-Meier survival analysis in subgroups stratified by SRS (B) or TMB (E) in the validation cohort with 58 GC patients. (C and F) Comparison of objective response rates in subgroups stratified by SRS (C) or TMB (F) in another validation cohort with 55 GC patients. GC, gastric cancer; TMB, tumor mutation burden; CI, confidence interval; HR, hazard ratio; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease

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Biology of Sex Differences

ISSN: 2042-6410

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