Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortex

Table 5 Total charge transferred by AMPA- and GABA-mediated events in aIC and pIC of both sexes

Measure	Area	Sex	Median	MAX	MIN	n/N	Two-way Anova Main effects and interactions	Multiple comparison (Šidák’s post hoc test)
sEPSCs Total charge (-pC)	aIC	M	− 180,894	− 60,757	− 235,773	12/10	Interaction: p = 0.1101 Area: F (1. 53) = 3.680 p = 0.06 Sex: F (1. 53) = 1.017 p = 0.3178	aIC Male vs pIC Male p = 0.0216 aIC Female vs pIC Female p = 0.9756 aIC Male vs aIC Female p = 0.1688 pIC Male vs pIC Female p = 0.8692
	aIC	F	− 117,082	− 28,617	− 205,287	13/10
	pIC	M	− 88,857	− 21,648	− 233,047	22/15
	pIC	F	− 105,611	− 27,801	− 199,381	12/10
sIPSCs Total charge (-pC)	aIC	M	− 453,628	− 115,748	− 1,275,617	19/11	Interaction: p = 0.2221 Area: F (1. 57) = 0.1999 p = 0.6565 Sex: F (1. 57) = 1.486 p = 0.2278	aIC Male vs pIC Male p = > 0.9999 aIC Female vs pIC Female p = 0.9756 aIC Male vs aIC Female p = 0.4082 pIC Male vs pIC Female p = 0.1789
	aIC	F	− 398,812	− 255,849	− 833,222	13/10
	pIC	M	− 319,953	− 89,489	− 692,799	13/9
	pIC	F	− 481,728	− 43,312	− 1,263,915	16/10

ISSN: 2042-6410