Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortex

Table 4 Intrinsic excitability of aIC and pIC pyramidal neurons in both sexes

Measure	Sex	Injected	aIC			pIC			p value Multiple Mann–Whitney Unpaired t test
(unit)		Current(pA)	Mean	SEM	n/N	Mean	SEM	n/N
Number of APs	Male	0	0	0	14/10	0	0	20/15	> 0.999999
		50	0.07	0.07		1.05	0.42		0.12
		100	1.36	0.73		4.75	1.18		0.09
		150	3.93	0.96		9.95	1.57		0.01
		200	6.36	1.51		14.95	1.78		0.003
		250	9	1.61		19.15	1.95		0.001
		300	12.07	1.56		21.95	1.97		0.001
		350	14.64	1.41		23.25	2.14		0.008
		400	17	1.28		23.45	2.14		0.02
		450	18.43	1.2		23	2.42		0.07
		500	19.5	1.13		22.85	2.45		0.11
		550	21	1.15		22.85	2.71		0.43
		600	21	1.26		19.35	3.14		0.67
	Female	0	0	0	14/6	0	0	16/12	> 0.999999
		50	0	0		0.94	0.48		0.10
		100	0.14	0.1		3.13	1.03		0.02
		150	1.43	0.6		6.5	1.44		0.008
		200	3.79	1.06		9.81	1.64		0.008
		250	6.86	1.23		13.25	1.47		0.005
		300	9.79	1.31		15.88	1.33		0.002
		350	12.29	1.41		18.06	1.27		0.005
		400	14	1.51		19.63	1.2		0.006
		450	15.86	1.61		20.94	1.09		0.02
		500	17.5	1.44		21.38	0.9		0.04
		550	19.21	1.34		21.63	1.14		0.18
		600	20.21	1.2		16.88	1.88		0.22

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