Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortex

Table 2 Voltage membrane response per current steps in aIC and pIC pyramidal neurons in both sexes

Measure (unit)	Condition	Injected current (pA)	aIC			pIC			p value Multiple Mann–Whitney Unpaired t test
			Mean	SEM	n/N	Mean	SEM	n/N
Voltage changes per current step (ΔVm)	Male	− 400	− 30.53	2.28	14/10	− 36.5	3.14	28/15	0.34
		− 350	− 27.98	2.18		− 32.99	2.83		0.39
		− 300	− 24.89	1.98		− 29.29	2.51		0.35
		− 250	− 21.98	1.8		− 25.65	2.22		0.37
		− 200	− 18.51	1.6		− 21.46	1.85		0.39
		− 150	− 14.77	1.31		− 16.94	1.5		0.47
		− 100	− 10.62	1		− 12.15	1.13		0.59
		− 50	− 5.68	0.58		− 6.49	0.63		0.47
		0	0.05	0.04		0.16	0.06		0.07
		50	7.62	1.21		8.13	0.93		0.66
		100	15.21	1.68		14.58	1.19		0.88
	Female	− 400	− 28.93	1.65	13/6	− 37.23	1.94	20/12	0.003
		− 350	− 26.19	1.6		− 33.91	1.78		0.001
		− 300	− 22.97	1.21		− 30.23	1.61		0.002
		− 250	− 20.08	1.2		− 26.34	1.43		0.003
		− 200	− 16.75	1.1		− 22.33	1.28		0.003
		− 150	− 13.31	0.86		− 17.74	1.1		0.006
		− 100	− 9.3	0.62		− 12.68	0.86		0.01
		− 50	− 5.01	0.38		− 6.85	0.55		0.02
		0	0.09	0.08		0.21	0.15		0.34
		50	5.52	0.47		8.74	0.97		0.07
		100	11.92	0.99		18.63	2.57		0.02

ISSN: 2042-6410