Table 1 Active and passive membrane properties of aIC and pIC pyramidal neurons in both sexes
From: Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortex
Misure | Area | Sex | Median | MAX | MIN | n/N | Two-way Anova Main effects and interactions | Multiple comparison (Šidák’s post hoc test) |
|---|---|---|---|---|---|---|---|---|
Cm (pA/pF) | aIC | M | 205.9 | 294 | 95.67 | 14/10 | Interaction: p = 0.9586 Area: F (1.65) = 15.93 p = 0.0002 Sex: F (1.65) = 1.323 p = 0.2543 | aIC Male vs pIC Male p = 0.0103 aIC Female vs pIC Female p = 0.0153 aIC Male vs aIC Female p = 0.7007 pIC Male vs pIC Female p = 0.6001 |
F | 200.2 | 302.1 | 82.38 | 13/6 | ||||
pIC | M | 92.73 | 271.8 | 21.66 | 28/15 | |||
F | 102.1 | 235.2 | 28.54 | 20/12 | ||||
Vr (mV) | aIC | M | − 73.45 | − 66 | − 79.07 | 14/10 | Interaction: p = 0.4244 Area: F (1.70) = 39.08 p = < 0.000 Sex: F (1.70) = 1.791 p = 0.1852 | aIC Male vs pIC Male p = 0.0002 aIC Female vs pIC Female p = < 0.0001 aIC Male vs aIC Female p = 0.3378 pIC Male vs pIC Female p = 0.8815 |
F | − 75.34 | − 71.75 | − 80.78 | 13/6 | ||||
pIC | M | − 67.19 | − 60 | − 76 | 28/15 | |||
F | − 69.69 | − 57.34 | − 78.22 | 20/12 | ||||
Rh (pA) | aIC | M | 125 | 240 | 50 | 14/10 | Interaction: p = 0.3339 Area: F (1.69) = 35.52 p = < 0.0001 Sex: F (1.69) = 5.301 p = 0.0243 | aIC Male vs pIC Male p = 0.0010 aIC Female vs pIC Female p = < 0.0001 aIC Male vs aIC Female p = 0.0828 pIC Male vs pIC Female p = 0.4825 |
F | 190 | 280 | 120 | 13/6 | ||||
pIC | M | 90 | 160 | 30 | 28/15 | |||
F | 80 | 220 | 20 | 20/12 | ||||
Number of APs (+ 150 pA) | aIC | M | 3.5 | 10 | 0 | 10/14 | Interaction: p = 0.5648 Area: F (1. 60) = 18.33 p = < 0.0001 Sex: F (1. 60) = 6.156 p = 0.0159 | aIC Male vs pIC Male p = 0.0019 aIC Female vs pIC Female p = 0.0241 aIC Male vs aIC Female p = 0.3748 pIC Male vs pIC Female p = 0.0480 |
F | 0 | 6 | 0 | 6/13 | ||||
pIC | M | 8 | 23 | 0 | 15/28 | |||
F | 4 | 18 | 0 | 12/20 |