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Fig. 6 | Biology of Sex Differences

Fig. 6

From: Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortex

Fig. 6

Differences in excitatory synaptic activity in female insular pyramidal neurons by region. A, B Representative spontaneous excitatory postsynaptic currents (sEPSCs) recorded at − 70 mV in female aIC and pIC. C, D On average, excitatory events are comparable in amplitude and frequency in both aIC and pIC. E, F Log-normal curve fittings with confidence intervals (± CI) reveal higher proportion of smaller and more frequent events in the aIC as compared to the pIC. Data are presented as box-and-whisker plots (minimum, maximum, median) and analyzed via Mann–Whitney U test. P-values < 0.05 are depicted in the graphs. The sample size for aIC female was 13/6, and for pIC female was 17/12

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