Fig. 5
From: Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortex
Region-specific spontaneous excitatory synaptic activity in adult male IC pyramidal neurons. A, B Representative spontaneous excitatory postsynaptic currents (sEPSCs) recorded at − 70 mV in male aIC and pIC. C, D On average, excitatory events are larger and less frequent in the pIC than the aIC. E, F Log-normal curve fittings with confidence intervals (± CI) reveal that the amplitude and frequency distribution are skewed to the right in the pIC as compared to the aIC. Data are presented as box-and-whisker plots (minimum, maximum, median) and analyzed via Mann–Whitney U test. P-values < 0.05 are depicted in the graphs. The sample size for aIC male was 14/9, and for pIC male was 27/16