Fig. 8

Sex differences in the gut microbial composition at genus level before and after SPS. A Venn diagram depicting shared and sex specific genera, B heat map of the genera which showed significant pre-existing group differences in each sex as well as in both sexes, C relative abundance of Lactobacillus, D relative abundance of Lachnospiraceae_Incertae_Sedis, E heat map of the genera which showed significant SPS-induced group differences in each sex and in both sexes, F relative abundance of Barnesiella. Due to technical difficulties stool samples were not collected from every single animal. Each symbol represents the value for an individual animal. Before SPS (blue bars—males control n = 6, SPS-R n = 5, SPS-S n = 5; pink bars—females control n = 9, SPS-R n = 6, SPS-S n = 7/6), following SPS (blue bars—males control n = 6, SPS-R n = 5, SPS-S n = 4; pink bars—females control n = 7, SPS-R n = 7, SPS-S n = 6)