Fig. 2

Sex differences in anxiety-like behavior and social impairments following SPS. Anxiety-like behavior tested on EPM: A Anxiety Index before group subdivisions, B Anxiety Index following group subdivisions, C % duration in open arms (OA), D % entries into open arms (OA). Anxiety-like behavior tested on OF: E duration in the center of the arena, F number of entries into the center of the arena, G number of rears. Social behavior tested on SI: H time spent interacting with a juvenile rat of same sex, I number of interactions initiated by the test rat towards the juvenile rat. Each symbol represents the value for an individual animal (blue bars—males: control n = 10, SPS-R n = 7, SPS-S n = 7; pink bars—females: control n = 10, SPS-R n = 8, SPS-S n = 6)