Fig. 3

Breast microbiota in male and female tumor tissues compared with matched non-pathological adjacent tissues. A Segment plots displaying alpha diversity indices (Chao1 index, Shannon index and evenness). The numbers in the top left corner represent counts of decreased (blue) and increased (yellow) measurements for paired samples. B Principal coordinates analysis (PCoA) according to the Bray–Curtis beta-diversity metric of male and female breast tissues. C Circular heatmap representing the differentially abundant taxa in male tumor versus non-pathological adjacent tissues: concentric circles represent taxonomic ranks from kingdom to genus; yellow shades indicate positive logFC values, whereas blue shades indicate negative logFC values correlations; the intensity of colors is proportional to logFC values. FH female adjacent non-pathological samples, FT female tumor samples, MH male adjacent non-pathological samples, MT male tumor samples. K kingdom, P phylum, C class, O order, F family, G genus, FC fold change