Fig. 2
Influence (R2) of genes and parental history of diabetes on T2D development. MLR analysis stratified by age at T2D diagnosis and sex demonstrates A the effect of groups of genes, B parental history, and C both factors on T2D development (early diagnosis, ≤ 45 years; late diagnosis, ≥ 46 years). Group 1, genes associated with insulin production located in the chromosome region 11p15.5; Group 2, genes associated with insulin production located in other chromosomes; Group 3, genes associated with peripheral insulin resistance; Group 4, genes associated with inflammation, and other functions. The power (1 − β error probability) > 0.99 for all MLR models. MLR multivariate logistic regression, SNP single nucleotide polymorphism, T2D type 2 diabetes