Stage | PreT (ms) | LH (ms) | ML (ms) | setNH (ms) | Rats # M/F | Trial ratio Go:NoGo | Success criteria | Consolidation days |
|---|
Go% | NoGo% |
|---|
G1 | 10–1500 | 2000 | 2000 | 0–400 | 46/51 | 0:1 | N/A | 70 | 4 |
G2 | 50–100 | 2000 | 2000 | 400 | 43/49 | 2:3 | 55 | 60 | 4 |
G3 | 50–100 | 2000 | 2000 | 400 | 40/47 | 1:1 | 70 | 70 | 2 |
G4 | 80–300 | 1500 | 1500 | 450 | 36/40 | 1:1 | 70 | 70 | 2 |
G5 | 150–500 | 1300 | 1300 | 500 | 34/36 | 1:1 | 70 | 70 | 2 |
G6 | 200–800 | 1000 | 1000 | 550 | 32/32 | 1:1 | 70 | 70 | 2 |
G7 | 400–1000 | 800 | 800 | 600 | 28/32 | 1:1 | 70 | 70 | 2 |
G8 | 500–1200 | 700 | 700 | 600 | 25/28 | 2:1 | 70 | 70 | 2 |
G9 | 500–1500 | 600 | 600 | 600 | 25/26 | 2:1 | 70 | 70 | 6 |
R1 | 500–1500 | 600 | 600 | 600 | 15/9 | 2:1 | 70 | 70 | 2–4 |
R2 | 500–1500 | 600 | 600 | 600 | 11/7 | 2:1 | 70 | 70 | 2–4 |
R3 | 500–1500 | 600 | 600 | 600 | 11/7 | 2:1 | 70 | 70 | 2–4 |
R4 | 500–1500 | 600 | 600 | 600 | 10/7 | 2:1 | 70 | 70 | 2–4 |
- G1–G9: regular Go/NoGo task stages; R1–R4: reversal Go/NoGo task stages. PreT: a randomly generated delay time between center nose port entry and audio cue onset; specific PreT ranges were shown in the table for each stage. For stage G1, the initial PreT range was set to 10–50 ms, the lower and upper limits were increased for 10 ms and 20 ms, respectively, after each correct trial till the range reached to 500–1500 ms. LH: limited holding time, the time limit within which the rats were allowed to stay in the entered center port after Go cues. ML: movement limit time, the time limit within which the rats had to enter one of the adjacent side ports after pulling out from the center port in the Go trial. setNH: setting NoGo holding time, the minimal time required the rats to hold still in the entered center port in the NoGo trials after the audio cue. For stage G1, the initial setNH was 0 and increased for 5 ms after each correct trial before reaching 400 ms. Rats #: the number of rats for male and female in each stage. Trial ratio: the ratio of Go and NoGo trials in each stage. For stage G1, the session contained only NoGo trials. Success criteria: the empirical setting criteria (correct rate for Go and NoGo trials within session) to judge the rats mastered each stage. Consolidation days: additional training length after the rat reached the setting success criteria
