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Fig. 7 | Biology of Sex Differences

Fig. 7

From: Sex differences in learning and performing the Go/NoGo tasks

Fig. 7

Averaged trials per session and regression model for RT and MT with the averaged trials. a Averaged number of trials per session for stage G2 (mean ± SD). The female rats performed significantly less trials in average than the male rats (Student’s t-test, p = 3.18 × 10–4). b Linear regression model with categorical covariates was used to test if the RTs can be significantly affected by the number of trials per session in stage G2. The fitted regression model for male rats was: mRT = 449.41–0.10*Trials. The fitted regression model for female rats was: fRT = 405.38 + 0.03*Trials. The overall regression was not statistically significant (R2 = 0.05, F(1,81) = 1.38 and p = 0.25). The slopes of fitted models are similar for male and female rats (F(1,81) = 1.19 and p = 0.28). c Linear regression model with categorical covariates was used to test if the MTs can be significantly affected by the number of trials per session in stage G2. The fitted regression model for male rats was: mMT = 630.48–0.33*Trials. The fitted regression model for female rats was: fMT = 427.51 + 0.18*Trials. The overall regression was not statistically significant (R2 = 0.08, F(1,81) = 2.39 and p = 0.05). The slopes of fitted models are not statistically different for male and female rats (F(1,81) = 3.85 and p = 0.05). d Averaged number of trials per session for stage G3–9 (mean ± SD). The female rats performed significantly less trials in average than the male rats (Student’s t-test, p = 1.81 × 10–4). e Linear regression model with categorical covariates was used to test if the RTs can be significantly affected by the number of trials per session in stage G3–9. The fitted regression model for male rats was: mRT = 319.18–0.005*Trials. The fitted regression model for female rats was: fRT = 287.08 + 0.15*Trials. The overall regression was not statistically significant (R2 = 0.06, F(1,72) = 1.58 and p = 0.20). The slopes of fitted models are similar for male and female rats (F(1,72) = 0.81 and p = 0.37). f Linear regression model with categorical covariates was used to test if the MTs can be significantly affected by the number of trials per session in stage G3–9. The fitted regression model for male rats was: mMT = 239.68 + 0.10*Trials. The fitted regression model for female rats was: fMT = 256.13 + 0.12*Trials. The overall regression was not statistically significant (R2 = 0.05, F(1,72) = 1.25 and p = 0.30). The slopes of fitted models are similar for male and female rats (F(1,72) = 0.02 and p = 0.88). g Averaged number of trials per session for stage R1–4 (mean ± SD). The female rats performed significantly less trials in average than the male rats (Student’s t-test, p = 2.71 × 10–3). h Linear regression model with categorical covariates was used to test if the RTs can be significantly affected by the number of trials per session in stage R1–4. The fitted regression model for male rats was: mRT = 483.21–0.43*Trials. The fitted regression model for female rats was: fRT = 476.09–0.56*Trials. The overall regression was not statistically significant (R2 = 0.09, F(1,14) = 0.45 and p = 0.72). The slopes of fitted models are similar for male and female rats (F(1,14) = 0.002 and p = 0.96). i Linear regression model with categorical covariates was used to test if the MTs can be significantly affected by the number of trials per session in stage R1–4. The fitted regression model for male rats was: mMT = 334.20–0.16*Trials. The fitted regression model for female rats was: fMT = 422.49–0.47*Trials. The overall regression was not statistically significant (R2 = 0.07, F(1,14) = 0.33 and p = 0.80). The slopes of fitted models are similar for male and female rats (F(1,14) = 0.06 and p = 0.81)

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