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Fig. 5 | Biology of Sex Differences

Fig. 5

From: Sex differences in learning and performing the Go/NoGo tasks

Fig. 5

Overall performances for retired rats. a Plot of correct Go rates as a function of correct NoGo rates for all retired rats (Nmale = 21; Nfemale = 26). b Comparisons of the correct Go rates before and after the Go-preference developed for the retired rats (mean ± SEM). Both retired male and female rats exhibited significantly higher correct Go rates after Go-preference developed (pMale = 1.29 × 10–7 and pFemale = 1.39 × 10–6). c Comparisons of the correct NoGo rates before and after the Go-preference developed for the retired rats (mean ± SEM). Both retired male and female rats exhibited significantly lower correct NoGo rates after Go-preference developed (pMale = 5.74 × 10–10 and pFemale = 2.62 × 10–10). d Comparisons of overall correct rates for the retired rats before and after the Go-preference developed (mean ± SEM). No significant difference was observed for both retired male and female rats (pMale = 0.92 and pFemale = 0.93). e, f Cumulative distribution of RTs before and after the Go-preference developed for retired rats. The RTs were significantly shortened after Go-preference developed for male (p = 7.96 × 10–127 with an effect size of 1.97) and female (p = 1.47 × 10–132 with an effect size of 2.41) rats, respectively. g–h Cumulative distribution of MTs before and after the Go-preference developed for retired rats. The MTs were significantly shortened after Go-preference developed for male (p = 1.27 × 10–75 with an effect size of 1.04) and female (p = 1.43 × 10–75 with an effect size of 1.38) rats, respectively. i–j Comparison of cumulative distributions of RTs of retired rats with Go-preference and rats in stage G9. The RTs were significantly shortened for Go-preference retired male rats (p = 3.62 × 10–47 with an effect size of − 0.55) and female rats (p = 4.17 × 10–51 with an effect size of − 0.22) than the rats in stage G9. k–l Comparison of cumulative distributions of MTs for retired rats with Go-preference and rats in stage G9. The MTs were significantly shortened for Go-preference retired male rats (p = 9.85 × 10–35 with an effect size of − 0.80) and female rats (p = 1.73 × 10–29 with an effect size of − 0.54) than the rats in stage G9. m Comparison of cumulative distributions of RTs of retired male and female rats with Go-preference. The RTs were significantly shortened for retired male rats than retired female rats (p = 4.17 × 10–51 with an effect size of − 0.43). n Comparison of cumulative distributions of MTs of retired male and female rats with Go-preference. The MTs were significantly shortened for retired male rats than retired female rats (p = 9.85 × 10–35 with an effect size of − 0.40). Two-way ANOVA with repeated measures and post hoc Holm–Sidak tests were used for b–d. Wilcoxon signed rank test was used for e–n. For Fig. b–n, Nmale = 15 and Nfemale = 14

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