Fig. 5

WCGNA-based Comparisons of the Consensus Modules to EV WGCNA-identified and Cell WGCNA-identified Modules. A Schematic diagram for the consensus WGCNA process. B Color-coded correspondence table of EV sample WGCNA-identified modules and the EV-Cell consensus modules indicates that most EV sample WGCNA-identified modules have a consensus counterpart, except for EV ‘darkgreen’ module (magenta box with arrow) which is unique to EVs. C Color-coded correspondence table of Cell sample WGCNA-identified modules and the EV-Cell Consensus modules indicates that most cell sample WGCNA-identified modules have a consensus counterpart. However, Cell ‘darkgreen’ (orange box with arrow, unrelated to EV ‘darkgreen’), exhibits minor overlap with EV-Cell Consensus modules ‘darkgrey’ and ‘yellow’, representing a nearly unique Cell module. Numbers in the table indicate gene counts in the intersection of the corresponding modules. Coloring of the table encodes − log(p), with p being the Fisher’s exact test p value for the overlap of the two modules. The grey module represents residual genes that could not be associated with networks