Lipidomic landscape of circulating extracellular vesicles isolated from adolescents exposed to ethanol intoxication: a sex difference study

Table 4 Summary of lipids with significant abundance using both ion modes in TLR4-KO mice

Mouse	Ion mode	EEF¹			EEM¹			SEI²
Mouse	Ion mode	LFC > 0	LFC < 0	Total	LFC > 0	LFC < 0	Total	LFC > 0	LFC < 0	Total
TLR4-KO	Negative	25	38	63	15	7	22	1	0	1
TLR4-KO	Positive	2	1	3	22	14	36	2	0	2
Total		27	39	66	37	21	58	3	0	3

Significant lipids separated according to the sign of their log fold-change (LFC). ¹In EEF and EEM comparisons, LFC > 0 columns = differential abundance in lipids increased after ethanol treatment; LFC < 0 columns = differential abundance in lipids decreased after ethanol treatment.²In SEI, LFC > 0 columns = differential abundance in lipids increased in females; LFC < 0 columns = differential abundance in lipids increased in males

ISSN: 2042-6410