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Fig. 8 | Biology of Sex Differences

Fig. 8

From: Sex-divergent effects on the NAD+-dependent deacetylase sirtuin signaling across the olfactory–entorhinal–amygdaloid axis in Alzheimer’s and Parkinson’s diseases

Fig. 8

Differential sex-associated changes in Sirtuin (SIRT) signaling across the olfactory bulb, olfactory tract, entorhinal cortex and amygdala in AD and PD. A Protein expression of SIRT family (SIRT1, 2, 3 and 5) across the olfactory axis in AD. B Protein expression of SIRT family (SIRT1, 2, 3 and 5) across the olfactory axis in PD. Western-blotting were performed in n = 2–6/group/structure (Additional file 1: Table S1). Representative images are shown. Equal loading of the gels was assessed by stain-free digitalization. Panels show histograms of band densities. Data are presented as mean ± SEM. *P < 0.05 vs. control group; **P < 0.01 vs. control group (a.u: arbitrary units)

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Biology of Sex Differences

ISSN: 2042-6410

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