Effect of progesterone administration in male and female smokers on nicotine withdrawal and neural response to smoking cues: role of progesterone conversion to allopregnanolone

Table 9 Main effects allopregnanolone:progesterone ratio and sex on neural activation when viewing smoking cues (minus neutral cues) in regions that did not show a significant interaction effect in Table 8

Outcome	Effect of log(allo/prog)	p value	Effect of sex [ref: female] (95% CI)	p value
PCC	− 0.02 (− 0.10, 0.06)	0.564	0.14 (0.00, 0.28)	0.048^a
ACC	− 0.03 (− 0.09, 0.02)	0.243	0.07 (− 0.06, 0.20)	0.292
Lateral occipital cortex (left)	− 0.03 (− 0.10, 0.03)	0.318	0.09 (− 0.02, 0.21)	0.122
Middle temporal gyrus (left)	− 0.01 (− 0.07, 0.06)	0.837	0.09 (− 0.03, 0.21)	0.160

ISSN: 2042-6410