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Fig. 2 | Biology of Sex Differences

Fig. 2

From: miR21 deletion in osteocytes has direct and indirect effects on skeletal muscle in a sex-dimorphic manner in mice

Fig. 2

Sex, but not genotype, affects grip strength and maximum force, whereas deletion of osteocytic miR21 only affects time to ½ relaxation in male OtmiR21Δ mice. In vivo grip strength (A) and plantar flexion (B, C) measurements from female and male OtmiR21Δ and miR21fl/fl mice (N = 6–11/group). Two-way ANOVA analyses were used to determine significant differences (Additional file 2: Table S2) *p < 0.05 compared to sex-matched miR21fl/fl controls, #p < 0.05 for overall male versus female comparisons, and £p < 0.05 compared to females of the same genotype

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Biology of Sex Differences

ISSN: 2042-6410

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