Sex-biased and parental allele-specific gene regulation by KDM6A

Table 1 Sex-biased gene expression in wt and Kdm6a KO clones

Genes were determined to be sex-biased in wt cells based on a ≥ twofold TPM difference cut off. Wt lists the number of female- and male-biased genes in BC and CB clones. Loss and Gain indicate the number and percentage of female- and male-biased genes that were lost or gained in KO clones. For CB cells, changes in sex-biased genes were determined by comparing values from CB Kdm6a KO cells to wt values from published data following quantile normalization (see Methods) [34]. See also Fig. 2 and Additional file 3

ISSN: 2042-6410