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Fig. 2 | Biology of Sex Differences

Fig. 2

From: Sex-biased and parental allele-specific gene regulation by KDM6A

Fig. 2

Sex-biased gene expression changes in BC Kdm6a KO cells. (A) Number of genes with sex-biased expression (≥ twofold TPM difference cut off; p < 0.05) in BC wt and Kdm6aΔ/Y clones. Overall, there was a greater loss of female-biased genes (pink) than male-biased genes (blue). See also Table 1 and Additional file 10A, B. (B) GO analysis of genes with loss of sex-biased expression in Kdm6aΔ/Y. Numbers in parentheses represent the fold enrichment over expected number of genes within a given biological process, while those not in parentheses represent the number of genes in each category

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