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Table 2 Cardiac magnetic resonance data before and after ASA according to sex

From: Sex-related differences in left ventricular remodeling and outcome after alcohol septal ablation in hypertrophic obstructive cardiomyopathy: insights from cardiovascular magnetic resonance imaging

 

Men (n = 54)

Women (n = 53)

p value for sex difference

Septal thickness (mm)

   

 Baseline

21.0 ± 1.8

21.5 ± 2.8

0.419

 Follow-up

15.1 ± 1.5

16.5 ± 2.7

0.009

 Changes

5.9 ± 1.6

5.0 ± 1.5

0.013

 p value

 < 0.001

 < 0.001

 

Posterior wall thickness (mm)

   

 Baseline

10.2 ± 1.4

10.9 ± 1.8

0.046

 Follow-up

8.6 ± 1.1

9.8 ± 1.6

 < 0.001

 Changes

1.6 ± 0.7

1.1 ± 0.7

0.005

 p value

 < 0.001

 < 0.001

 

LVM index (g/m2)

   

 Baseline

95.1 ± 15.6

108.6 ± 16.6

0.001

 Follow-up

80.8 ± 15.7

97.1 ± 15.9

 < 0.001

 Changes

14.3 ± 4.1

11.4 ± 1.9

0.001

 p value

 < 0.001

 < 0.001

 

Post-ablation infarct (g)

11.2 ± 2.8

7.8 ± 2.2

 < 0.001

LVM reduction ratio, %

15.3 ± 4.3

10.7 ± 1.8

 < 0.001

LVEDV index (g/m2)

   

 Baseline

69.5 ± 7.2

66.8 ± 7.6

0.129

 Follow-up

77.0 ± 7.6

72.2 ± 6.9

0.006

 Changes

7.5 ± 2.3

5.4 ± 1.3

 < 0.001

 p value

 < 0.001

 < 0.001

 

LVESV index (ml/m2)

   

 Baseline

24.8 ± 2.9

21.8 ± 2.9

0.006

 Follow-up

26.5 ± 3.3

23.2 ± 2.7

 < 0.001

 Changes

1.7 ± 0.8

1.4 ± 0.7

0.102

 p value

 < 0.001

 < 0.001

 

EF (%)

   

 Baseline

64.1 ± 3.5

67.2 ± 4.4

0.002

 Follow-up

65.5 ± 3.6

67.8 ± 3.9

0.014

 Changes

1.4 ± 0.04

0.5 ± 0.02

0.015

 p value

 < 0.001

0.006

 

Remote LGE (g)

   

 Baseline

9.9 ± 2.9

12.2 ± 2.3

0.001

 Follow-up

9.9 ± 2.9

12.3 ± 2.3

0.001

 Changes

0.05 ± 0.19

0.10 ± 0.36

0.433

 p value

0.153

0.100

 

LVOTG (mmHg)

   

 Baseline

90.6 ± 10.9

100.1 ± 18.9

0.012

 Follow-up

15.2 ± 8.4

31.1 ± 9.1

 < 0.001

 Changes

75.4 ± 9.5

68.9 ± 13.3

0.022

 p value

 < 0.001

 < 0.001

 
  1. LV left ventricular, LVM left ventricular mass, EDV end-diastolic volume, ESV end-systolic volume, EF ejection fraction, LGE late gadolinium enhancement, LVOTG left ventricular outflow tract gradient