Table 1 Baseline clinical and echocardiographic characteristics
Men (n = 54) | Women (n = 53) | p Value | |
|---|---|---|---|
Age (year) | 47 ± 8 | 55 ± 6 | < 0.001 |
BSA (m2) | 1.9 ± 0.1 | 1.8 ± 0.1 | < 0.001 |
HR (bpm) | 77 ± 9 | 74 ± 9 | 0.338 |
SBP (mm Hg) | 129 ± 12 | 132 ± 17 | 0.382 |
DBP (mm Hg) | 73 ± 12 | 75 ± 13 | 0.342 |
Menopausal status | NA | 48 (90.6%) | |
NYHA (median) | 2 (1, 4) | 3 (2, 4) | < 0.001 |
Hypertension | 3 (5.6%) | 4 (7.5%) | 0.677 |
Diabetes | 3 (5.6%) | 2 (3.8%) | 0.662 |
Nonsustained VT | 5 (9.3%) | 6 (11.3%) | 0.974 |
Chest pain | 11 (20.4%) | 20 (37.7%) | 0.077 |
Dyspnea | 27 (50.0%) | 39 (73.6%) | 0.021 |
Syncope | 4 (7.4%) | 3 (5.7%) | 0.715 |
Family history of HCM or sudden death | 7 (12.9%) | 5 (9.4%) | 0.786 |
Medications | |||
Beta blockers | 32 (59.3%) | 27 (50.9%) | 0.503 |
Nondihydropyridine CCB | 8 (14.8%) | 15 (28.3%) | 0.144 |
ACEI/ARB | 8 (14.8%) | 13 (24.5%) | 0.307 |
Diuretics | 0 (0.0%) | 3 (5.7%) | 0.235 |
Moderate or severe MR | 28 (51.9%) | 39 (73.6%) | 0.037 |
Alcohol use | 2.3 ± 0.5 | 1.6 ± 0.4 | < 0.001 |