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Table 1 Demographics, clinical and surgical characteristics of the women versus men in the cohort before propensity score matching

From: Sex differences following percutaneous coronary intervention or coronary artery bypass surgery for acute myocardial infarction

Variable

PCI with stent

CABG

Women

(n = 13,514)

Men

(n = 46,693)

STD

Women

(n = 1762)

Men

(n = 5565)

STD

Age (years)

71.2 ± 11.7

61.8 ± 13.4

0.75

69.3 ± 9.9

65.2 ± 11.7

0.38

Comorbid conditions

      

 Diabetes mellitus

7374 (54.6%)

15,866 (34.0%)

0.42

1212 (68.8%)

2644 (47.5%)

0.44

 Hypertension

10,448 (77.3%)

27,716 (59.4%)

0.39

1420 (80.6%)

3734 (67.1%)

0.31

 Dyslipidemia

5901 (43.7%)

21,987 (47.1%)

− 0.07

681 (38.6%)

1942 (34.9%)

0.08

 Heart failure hospitalization

1647 (12.2%)

2041 (4.4%)

0.29

265 (15.0%)

435 (7.8%)

0.23

 Peripheral arterial disease

807 (6.0%)

1412 (3.0%)

0.14

137 (7.8%)

339 (6.1%)

0.07

 Prior stroke hospitalization

2550 (18.9%)

4998 (10.7%)

0.23

353 (20.0%)

901 (16.2%)

0.10

 COPD

945 (7.0%)

4203 (9.0%)

− 0.07

111 (6.3%)

678 (12.2%)

− 0.20

 Liver cirrhosis

245 (1.8%)

905 (1.9%)

− 0.01

19 (1.1%)

122 (2.2%)

− 0.09

 Malignancy

773 (5.7%)

1860 (4.0%)

0.08

60 (3.4%)

177 (3.2%)

0.01

 Autoimmune disease

434 (3.2%)

552 (1.2%)

0.14

43 (2.4%)

65 (1.2%)

0.10

 Chronic kidney disease

3689 (27.3%)

7024 (15.0%)

0.30

598 (33.9%)

1480 (26.6%)

0.16

 Dialysis

980 (7.3%)

1371 (2.9%)

0.20

115 (6.5%)

240 (4.3%)

0.10

Charlson’s Comorbidity Index score

3.4 ± 2.1

2.5 ± 1.8

0.47

3.8 ± 2.0

3.1 ± 2.0

0.32

Bleeding history

      

 Major bleeding

964 (7.1%)

2180 (4.7%)

0.10

94 (5.3%)

247 (4.4%)

0.04

 GI bleeding

2758 (20.4%)

5721 (12.3%)

0.22

305 (17.3%)

734 (13.2%)

0.11

 ICH

200 (1.5%)

548 (1.2%)

0.03

22 (1.2%)

56 (1.0%)

0.02

 Anemia

506 (3.7%)

608 (1.3%)

0.16

49 (2.8%)

73 (1.3%)

0.10

Hospital level

      

 Medical center (teaching hospital)

6454 (47.8%)

23,883 (51.1%)

− 0.07

1185 (67.3%)

3762 (67.6%)

− 0.01

 Regional/district hospital

7060 (52.2%)

22,810 (48.9%)

0.07

577 (32.7%)

1803 (32.4%)

0.01

Type of CABG

      

 On pump

–

–

–

1447 (82.1%)

4577 (82.2%)

 < 0.01

 Off pump

–

–

–

315 (17.9%)

988 (17.8%)

 < 0.01

Endarterectomy

   

79 (4.5%)

274 (4.9%)

− 0.02

Concomitant valve surgery

–

–

–

136 (7.7%)

316 (5.7%)

0.08

Valve location and type

      

 Aortic valve replacement

–

–

–

48 (2.7%)

131 (2.4%)

0.02

 Mitral valve repair

–

–

–

30 (1.7%)

80 (1.4%)

0.02

 Mitral valve replacement

–

–

–

60 (3.4%)

123 (2.2%)

0.07

Details of coronary stenting

      

 Type of stent

      

  BMS

10,076 (74.6%)

34,400 (73.7%)

0.02

–

–

–

  DES

3438 (25.4%)

12,293 (26.3%)

− 0.02

–

–

–

 Number of stenting

1.03 ± 0.17

1.03 ± 0.16

0.03

–

–

–

Number of intervened/grafted vessels

      

 1

10,118 (74.9%)

37,482 (80.3%)

− 0.13

134 (7.6%)

298 (5.4%)

0.09

 2

2984 (22.1%)

8201 (17.6%)

0.11

339 (19.2%)

911 (16.4%)

0.08

 3

412 (3.0%)

1010 (2.2%)

0.06

1289 (73.2%)

4356 (78.3%)

− 0.12

Antiplatelet therapy at discharge

      

 Aspirin

9675 (71.6%)

38,780 (83.1%)

− 0.28

665 (37.7%)

2597 (46.7%)

− 0.18

 Clopidogrel/ticlopidine

11,027 (81.6%)

41,574 (89.0%)

− 0.21

425 (24.1%)

1496 (26.9%)

− 0.06

 Antiplatelet therapy

      

  Single

4089 (30.3%)

8675 (18.6%)

0.27

1686 (95.7%)

5204 (93.5%)

0.10

  Dual

9425 (69.7%)

38,018 (81.4%)

− 0.27

76 (4.3%)

361 (6.5%)

− 0.10

Other medications at discharge

      

 Statin

6357 (47.0%)

26,159 (56.0%)

− 0.18

431 (24.5%)

1447 (26.0%)

− 0.04

 Beta-blocker

6909 (51.1%)

26,955 (57.7%)

− 0.13

563 (32.0%)

1934 (34.8%)

− 0.06

 ACEI/ARB

7683 (56.9%)

28,702 (61.5%)

− 0.09

528 (30.0%)

1492 (26.8%)

0.07

 OAC drugs

203 (1.5%)

792 (1.7%)

− 0.02

59 (3.3%)

251 (4.5%)

− 0.06

 OHA drugs

4457 (33.0%)

10,819 (23.2%)

0.22

604 (34.3%)

1557 (28.0%)

0.14

 Insulin

1333 (9.9%)

1753 (3.8%)

0.24

283 (16.1%)

437 (7.9%)

0.26

 PPI

901 (6.7%)

2233 (4.8%)

0.08

111 (6.3%)

299 (5.4%)

0.04

 NSAID

2763 (20.4%)

9253 (19.8%)

0.02

284 (16.1%)

1029 (18.5%)

− 0.06

Follow-up (years)

2.8 ± 2.7

3.4 ± 2.8

− 0.21

3.2 ± 3.4

3.8 ± 3.6

− 0.16

  1. Data were given as frequency (percentage) or mean ± standard deviation
  2. PCI percutaneous coronary intervention, CABG coronary artery bypass grafting, STD standardized difference, COPD chronic obstructive pulmonary disease, GI gastrointestinal, ICH intracranial haemorrhage, BMS bare metal stent, DES drug-eluting stent, ACEi angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, OAC oral anticoagulants, OHA oral hypoglycemic agent, PPI proton pump inhibitor