Fig. 3

The effects of sex, MetS, and exercise training on body weight, heart weight and tibia length at 10 months of age in sedentary and exercise-trained male (m) and female (f) standard diet-fed wild-type (SD/WT) and high-fat diet-fed APOB-100 transgenic (HFD/APOB-100) mice. A Representative images of the mice in each group, B Body weight, C Tibia length, D Heart weight, and E Heart weight to tibia length ratio. Values are mean ± SEM, n = 11–12/group, ^$p < 0.05, female vs. male groups, *p < 0.05, HFD/APOB-100 vs. SD/WT groups, ^#p < 0.05, ET vs. sedentary groups; Three-Way ANOVA (Holm-Sidak post hoc test)