Fig. 2

The effects of sex, MetS, and exercise training on serum laboratory parameters at 10 months of age in sedentary and exercise-trained male (m) and female (f) standard diet-fed wild-type (SD/WT) and high-fat diet-fed APOB-100 transgenic (HFD/APOB-100) mice. A Serum LDL-cholesterol level, B Serum HDL-cholesterol level, C Serum LDL/HDL-cholesterol ratio, and D HOMA-IR. Values are mean ± SEM, n = 11–12/group, ^$p < 0.05, female vs. male groups, *p < 0.05, HFD/APOB-100 vs. SD/WT groups, Three-Way ANOVA (Holm-Sidak post hoc test) in cases of serum LDL-cholesterol, serum HDL-cholesterol and serum LDL/HDL cholesterol ratio. In the case of HOMA-IR values, Kruskal–Wallis test (ANOVA on ranks) was used followed by Holm-Sidak post hoc test