Skip to main content

Table 4 Echocardiographic parameters in females 16 weeks after induction of Ampkα2 deletion by tamoxifen injection

From: Spatiotemporal AMPKα2 deletion in mice induces cardiac dysfunction, fibrosis and cardiolipin remodeling associated with mitochondrial dysfunction in males only

Echocardiographic parameters Ampkα2f/f n = 7 Ampkα2ciKO n = 6
HR (beats/min) 384 ± 30 447 ± 35
IVSd (mm) 0.97 ± 0.12 0.99 ± 0.09
IVSs (mm) 1.49 ± 0.12 1.56 ± 0.15
LVIDd (mm) 2.76 ± 0.21 2.55 ± 0.16
LVIDs (mm) 1.50 ± 0.16 1.30 ± 0.12
LVPWd (mm) 1.10 ± 0.07 1.03 ± 0.03
LVPWs (mm) 1.48 ± 0.08 1.46 ± 0.10
EDV (ml) 0.07 ± 0.01 0.05 ± 0.01
ESV (ml) 0.12 ± 0.02 0.09 ± 0.01
EF (%) 81.1 ± 4.4 82.4 ± 0.4
SV (ml) 0.05 ± 0.01 0.05 ± 0.01
FS (%) 45.4 ± 4.7 47.1 ± 1.0
CO (ml/min) 18.4 ± 4.3 21.2 ± 3.6
  1. HR, heart rate; IVSd, interventricular septal thickness at end-diastole; IVSs, interventricular septal thickness at end-systole; LVIDd, left ventricular internal dimension at end-diastole; LVIDs, left ventricular internal dimension at end-systole; LVWPd, left ventricular posterior wall thickness at end-diastole; LVWPs, left ventricular posterior wall thickness at end-systole; EDV, end-diastolic volume; ESV, end-systolic volume; EF, left ventricular ejection fraction; SV, stroke volume; FS, left ventricular fractional shortening; CO, cardiac output