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Fig. 7 | Biology of Sex Differences

Fig. 7

From: Spatiotemporal AMPKα2 deletion in mice induces cardiac dysfunction, fibrosis and cardiolipin remodeling associated with mitochondrial dysfunction in males only

Fig. 7

Left ventricular integration of electron transfer chain complex I within the mitochondrial supercomplexes 16 weeks after cardiac-specific Ampkα2 deletion induction in male and female mice. A Mitochondrial supercomplexes were first separated by BN-PAGE (left panels), then transferred to PVDF membrane and incubated with complex I antibody (right panels) in CT and KO males (upper panels) and females (lower panels). B Quantification of isolated complex I and complex I including supercomplexes in males (left panel) and females (right panel). (n = 4 per experimental group). *p < 0.05 Ampkα2f/f vs Ampkα2ciKO (same sex)

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Biology of Sex Differences

ISSN: 2042-6410

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