Parameter (unit) | Male | Female | p-value | |||
---|---|---|---|---|---|---|
Sham | CKD | Sham | CKD | CKD vs. sham | Female vs. male | |
IWTs (mm) | 3.07 ± 0.09 | 3.48 ± 0.21 | 3.31 ± 0.11 | 3.67 ± 0.14 | 0.051 | 0.373 |
IWTd (mm) | 1.86 ± 0.18 | 2.42 ± 0.33* | 1.72 ± 0.23 | 2.03 ± 0.09* | 0.011 | 0.066 |
PWTs (mm) | 3.00 ± 0.10 | 3.42 ± 0.24 | 3.24 ± 0.12 | 3.54 ± 0.18 | 0.089 | 0.602 |
PWTd (mm) | 1.74 ± 0.05 | 2.23 ± 0.25* | 1.82 ± 0.06 | 1.97 ± 0.14 | 0.038 | 0.203 |
SWTs (mm) | 3.26 ± 0.11 | 3.98 ± 0.21* | 3.32 ± 0.08 | 3.63 ± 0.12* |  < 0.001 | 0.074 |
SWTd (mm) | 2.02 ± 0.10 | 2.52 ± 0.18* | 1.69 ± 0.08# | 1.88 ± 0.07# | 0.006 |  < 0.001 |
LVEDD (mm) | 6.73 ± 0.17 | 6.50 ± 0.36 | 6.20 ± 0.14 | 6.41 ± 0.11 | 0.547 | 0.761 |
LVESD (mm) | 3.51 ± 0.17 | 2.92 ± 0.37 | 2.15 ± 0.19# | 2.07 ± 0.15# | 0.182 | 0.011 |
Heart rate (1/min) | 363 ± 6 | 347 ± 14 | 370 ± 12 | 379 ± 10 | 0.479 | 0.045 |
LVEDV (μL) | 102 ± 6 | 75 ± 6* | 89 ± 9 | 99 ± 6# | 0.029 | 0.031 |
LVESV (μL) | 33 ± 4 | 26 ± 3 | 36 ± 4 | 39 ± 3# | 0.377 | 0.021 |
SV (μL) | 70 ± 4 | 49 ± 5* | 53 ± 6 | 60 ± 4 | 0.011 | 0.120 |
CO (mL/min) | 25 ± 1 | 17 ± 2* | 19 ± 2# | 23 ± 1* | 0.003 | 0.013 |
SBP (mmHg) | 111 ± 6 | 120 ± 4 | 126 ± 6# | 136 ± 8# | 0.117 | 0.017 |
DBP (mmHg) | 87 ± 5 | 94 ± 4 | 98 ± 7# | 107 ± 8# | 0.215 | 0.048 |