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Fig. 6 | Biology of Sex Differences

Fig. 6

From: Activation of G protein-coupled estradiol receptor 1 in the dorsolateral striatum enhances motivation for cocaine and drug-induced reinstatement in female but not male rats

Fig. 6

GPER1 activation enhances cocaine-induced reinstatement in females but not males. G1-treated females have a significantly greater number of active pokes than CHOL-treated females (p = 0.0460), G1 males (p = 0.0241), and CHOL males (p = 0.0259). Data are presented as mean ± SEM. Individual data points presented as “X” indicate prior G1 treatment and individual data point presented as “+” indicate prior CHOL treatment, during weeks 3 and 4 of self-administration

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Biology of Sex Differences

ISSN: 2042-6410

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