A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta

Table 2 Linear modeling for sex-specific autosomal DNAme shows consistent higher male methylation

	Δβ > 0	Δβ > 0.05	Δβ > 0.10	Δβ > 0.20
FDR < 0.05	24,715 (0.74)	2,942 (0.87)	166 (0.92)	4 (1.00)
FDR < 0.01	14,108 (0.80)	2,682 (0.88)	166 (0.92)	4 (1.00)

Number of significantly differentially methylated autosomal positions at various statistical and biological thresholds are shown. FDR indicates the Benjamini-Hochberg false discovery rate, and Δβ refers to β value sex difference (male-female). Numbers in brackets indicate the proportion of sites at each threshold more highly methylated in male placentae

ISSN: 2042-6410