Fig. 1

Effect of MCAo on mortality, infarct volume, and sensory-motor ability in males and females. a Kaplan-Meier survival plot shows significantly greater mortality after MCAo in males as compared to females (p = 0.0014). b Representative images of TTC-stained brain sections from female and male rats 2 days after MCAo. c Histogram depicting mean (± SEM) of infarct volume (ns, not significant). Sensory-motor impairment assessed by d adhesive removal test (ART) and e the vibrissae-evoked forelimb placement task (VIB). a Main effect of stroke. b Main effect of sex. c Interaction effect; *p < 0.05