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Table 1 Basic characteristics and intervention results among men and women

From: Gender differences in the efficacy of pioglitazone treatment in nonalcoholic fatty liver disease patients with abnormal glucose metabolism

 

Men (n = 85)

Women (n = 70)

P value

Group, n (%)

  

0.220

 LSI

28 (32.94%)

25 (35.71%)

 

 PGZ + LSI

22 (25.88%)

25 (35.71%)

 

 BBR + LSI

35 (41.18%)

20 (28.57%)

 

Age (age)

49.62 ± 10.81

53.47 ± 7.68

0.013

Smoking, n (%)

23 (27.06%)

2 (2.86%)

< 0.001

Drinking, n (%)

25 (29.41%)

1 (1.43%)

< 0.001

Glucose metabolism

  

0.643

 IGR, n (%)

42 (49.41%)

37 (52.86%)

 

 T2DM, n (%)

43 (50.59%)

33 (47.14%)

Treatment adherence (%)

100 (15–100)

100 (32–100)

0.161

Baseline BMI (kg/m2)

28.0 ± 3.5

27.4 ± 4.0

0.301

Final BMI (kg/m2)

27.0 ± 3.1

26.5 ± 4.1

0.466

BMI changes (kg/m2)

− 1.1 ± 1.1a

− 0.9 ± 1.1a

0.270

Baseline LFC (%)

33.02 ± 13.70

36.01 ± 16.21

0.215

Final LFC (%)

19.65 ± 12.65

21.76 ± 15.79

0.357

Absolute changes of LFC (%)

− 13.35 ± 15.41a

− 14.27 ± 15.58a

0.714

 LSI (n = 53)

− 12.64 ± 17.78a

− 8.76 ± 13.49a

0.379

 PGZ + LSI (n = 47)

− 9.95 ± 15.18a

− 15.24 ± 14.54a

0.229

 BBR + LSI (n = 55)

− 16.06 ± 13.35a

− 19.95 ± 17.59a

0.359

  1. Data are given as means ± SD or median (Min-Max) for continuous variables and percentages for categorical variables. Absolute changes of LFC (%), the absolute changes separately in three groups or three groups combined. P value calculated by unpaired Student’s t test or Mann-Whitney U test for quantitative variables, and χ2 test or Fisher’s exact test for qualitative variables, differences between women and men
  2. IGR impaired glucose regulation, T2DM type 2 diabetes, BMI body mass index, LSI lifestyle intervention, PGZ pioglitazone, BBR berberine, LFC liver fat content
  3. aCalculated by paired t test, differences between before and after intervention