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Fig. 6 | Biology of Sex Differences

Fig. 6

From: Selective deletion of endothelial mineralocorticoid receptor protects from vascular dysfunction in sodium-restricted female mice

Fig. 6

Endothelial MR deletion protects female mice from sodium restriction-induced endothelial dysfunction and vascular constriction. Endothelial relaxation responses to acetylcholine (Ach) (a), endothelial-independent relaxation responses to sodium nitroprusside (SNP) (b), vascular constriction responses to phenylephrine (Phe) (c), serotonin (5-HT) (d), and KCl (e) in male and female WT and KO mice on NSD and SRD. Two-way ANOVA of dose-response curves with repeated measures (*P < 0.05, male NSD KO N = 4, male KO SRD N = 4, female KO NSD N = 6, female KO SRD N = 5)

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Biology of Sex Differences

ISSN: 2042-6410

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