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Table 2 In-hospital care and complications among dying individuals with COVID-19 according to sex

From: Sex differences in clinical phenotype and transitions of care among individuals dying of COVID-19 in Italy

 

Overall (n = 3517)

Women (n = 1171)

Men (n = 2346)

p value

Symptoms at admission, n (%)a

 Fever

2585 (76.3)

795 (71.3)

1790 (78.8)

< 0.001

 Shortness of breath

2491 (73.6)

794 (71.2)

1697 (74.7)

0.031

 Cough

1315 (38.8)

402 (36.1)

913 (40.2)

0.020

 Diarrhea

193 (5.7)

72 (6.5)

121 (5.3)

0.63

 Hemoptysis

19 (0.6)

5 (0.4)

14 (0.6)

0.18

Time (in days) from symptoms’ onset to; median [IQR]b

 Hospital admission

4 [2–7]

4 [2–7]

5 [2–7]

< 0.001

 In-hospital nasopharyngeal swab

5 [3–9]

5 [2–9]

6 [3–9]

0.007

 ICU

8 [5–12]

7 [4–12]

8 [5–12]

0.12

 In-hospital death

11 [7–17]

11 [7–16]

11 [7–17]

0.06

Length of stay (days), median [IQR]c

6 [3–11]

6 [3–11]

6 [3–11]

0.80

Admission in ICUd

667 (20.5)

149 (13.9)

518 (23.8)

< 0.001

In-hospital complicationse

 Acute respiratory distress syndrome

3248 (96.9)

1077 (96.4)

2171 (97.2)

0.24

 Acute renal injury

741 (22.1)

187 (16.7)

554 (24.8)

< 0.001

 Acute cardiac injury

368 (11.0)

101 (9.0)

267 (12.0)

0.012

 Co-infection

437 (13.0)

136 (12.2)

301 (13.5)

0.30

Shock

661 (19.7)

168 (15.0)

493 (22.1)

< 0.001

In-hospital treatments, n (%)f

 Antibiotics

2908 (85.8)

941 (84.3)

1967 (86.5)

0.08

 Antivirals (including hydroxychloroquine)

2019 (59.6)

583 (52.2)

1436 (63.2)

< 0.001

 Steroids

1293 (38.2)

414 (37.1)

879 (38.7)

0.39

 Tocilizumab

116 (3.9)

15 (1.5)

101 (5.1)

< 0.001

  1. aMissing data: n = 52 (1.5%)
  2. bMissing data: n = 628 (18%, time to hospital admission); n = 465 (13%, time to death); 747 (21%, time to testing)
  3. cMissing data: n = 64 (1.8%, time to death)
  4. dMissing data: n = 265 (7.5%)
  5. eMissing data, n = 166 (4.7%)
  6. fMissing data, n = 128 (3.6%)