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Table 3 Plasma total estrogen and testosterone (TES) of Int-control, CsX, CsX-TRT, CsX-LST, and CsX-LST-TRT male SD rats

From: Hypogonadal hypertension in male Sprague-Dawley rats is renin-angiotensin system-dependent: role of endogenous androgens

Group

Total estrogen (pg mL−1)

Testosterone (TES) (ng mL−1)

InT-control

30.7 ± 0.6

0.72 ± 0.2

CsX

30.9 ± 1.2

---- a

CsX-TRT

31.3 ± 0.5

0.96 ± 0.1

CsX-LST

32.7 ± 0.2

---- a

CsX-LST-TRT

33.2 ± 0.6

1.14 ± 0.1

  1. Male Sprague-Dawley (SD) rats: intact (InT-control), bilaterally castrated (CsX), and CsX with TES therapy (CsX-TRT; 1.75 mg kg−1; sc, 2x/week). In a separate experiment, CsX males were given drinking water with losartan (250 mg L−1) without TES therapy (CsX-LST) or with TES therapy (CsX-LST-TRT; 1.75 mg kg−1; sc, 2x/week). Data are means ± SEM (n = 6-13 rats per group). Neither total estrogen nor TES concentrations differed significantly among the five experimental groups (P > 0.05)
  2. aPlasma TES levels in CsX and CsX-LST groups were below the detectable limits of the radioimmunoassay
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Biology of Sex Differences

ISSN: 2042-6410

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