|
Group
|
Week 0, BW (g)
|
Week 10, BW (g)
|
Week 15, BW (g)
|
Seminal vesicle (g·100 g of BW−1)
|
|---|
|
InT-control
|
339 ± 8a+
|
433 ± 12a#
|
439 ± 14a#
|
0.29 ± 0.013a
|
|
CsX
|
383 ± 22b+
|
457 ± 22a#
|
458 ± 27a#
|
0.02 ± 0.001c
|
|
CsX-TRT
|
374 ± 7b+
|
433 ± 7a#
|
446 ± 8a#
|
0.33 ± 0.018a
|
|
CsX-DRT
|
519 ± 13c+
|
594 ± 17c#
|
670 ± 26c*
|
0.10 ± 0.003d
|
|
CsX-LST
|
385 ± 4b+
|
456 ± 8a#
|
462 ± 11a#
|
0.03 ± 0.001b
|
|
CsX-LST-TRT
|
374 ± 3b+
|
432 ± 4a#
|
453 ± 5a*
|
0.34 ± 0.025a
|
|
CsX-TRT-Tfm
|
401 ± 23b+
|
487 ± 16b#
|
525 ± 20b#
| |
- Male Sprague-Dawley (SD) rats: intact (InT), bilaterally castrated (CsX), and CsX with TES therapy (CsX-TRT; 1.75 mg kg−1; sc, 2x/week) or DHT therapy (CsX-DRT;1.00 mg kg−1; sc, 2x/week). In a separate experiment, CsX males were given losartan drinking water (250 mg L−1) without (CsX-LST) or with TES therapy (CsX-LST-TRT; 1.75 mg kg−1; sc, 2x/week). Testicular feminized male (Tfm) rats were castrated and given TES therapy (CsX-TRT-Tfm). Data are means ± SEM (n = 6-13 rats per group).
- a-cMean values within each column for BW (week 0, 10, and 15) and seminal vesicle weight without common superscript are significantly different (0.0001 ≤ P ≤ 0.02)
- +, #, *Mean values for BW within each row for each of the experimental groups (InT-control, CsX, CsX-TRT, CsX-DRT, CsX-LST, CsX-LST-TRT, and CsX-TRT-Tfm) over time (week 0, 10, and 15) without common superscript are significantly different (0.0001 ≤ P ≤ 0.02)
