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Fig. 5 | Biology of Sex Differences

Fig. 5

From: Sex difference in dopamine D1-D2 receptor complex expression and signaling affects depression- and anxiety-like behaviors

Fig. 5

The anxiogenic effects of SKF 83959 are correlated with low-frequency oscillations in NAc. a Correlation curves showing a significant linear correlation between NAc theta oscillatory power with open arm time in female rats following 0.1 mg/kg and 0.25 mg/kg SKF 83959. b Correlation curves showing the relationship between NAc theta oscillatory power with open arm time in male rats following 0.1 and 0.25 mg/kg SKF 83959. A significant correlation was observed only at 0.25 mg/kg dose. c Correlation curves showing NAc delta oscillatory power with open arm time in female rats following 0.1 and 0.25 mg/kg SKF 83959. NAc delta oscillatory power correlated with open arm time in female rats selectively following 0.1 mg/kg SKF 83959. d Correlation curves showing the relationship between NAc delta oscillatory power with open arm time in male rats following 0.1 and 0.25 mg/kg SKF 83959. NAc delta oscillatory power correlated with open arm time in male rats selectively following 0.25 mg/kg SKF 83959. Points represent values taken from individual electrodes with line of best fit shown. N = 5–6/group with two electrodes/rat

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Biology of Sex Differences

ISSN: 2042-6410

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