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Table 1 System functions of X/Y-linked genes according to the DEF approach

From: SeXY chromosomes and the immune system: reflections after a comparative study

Function

X

Y

nY/nX

PAR

nPAR/nX

 

n (%)r

n (%)r

r

n (%)r

r

Basal/ubiquitous/unknown

335 (40.0)

11 (17.5)

0.03

3 (16.7)

0.01

Development, proliferation, apoptosis

87 (10.4)3

7 (11.1)3

0.083

6 (33.3)2

0.072

Immune system

54 (6.5)4

10 (15.9)2

0.192

8 (44.4)1

0.151

Nervous system

108 (12.9)2

2 (3.2)4

0.025

0 (0)

 

Endocrine system

35 (4.2)5

1 (1.6)5

0.034

1 (5.6)3

0.033

Reproductive system

153 (18.3)1

32 (50.8)1

0.211

0 (0)

 

Other systems

65 (7.8)

0 (0)

 

0 (0)

 

TOTAL or average

837 (100)

63 (100)

0.09

18 (100)

0.06

  1. * Other systems include the digestive, respiratory, cardiovascular, integumentary, urinary, and musculoskeletal systems; r, Rank. The classes ´Basal/ubiquitous/unknown´ and ´Other systems´ do not participate in the ranking to avoid bias due to undefined genes or because the genes may belong to different classes.