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Fig. 2 | Biology of Sex Differences

Fig. 2

From: The angiotensin II type I receptor contributes to impaired cerebral blood flow autoregulation caused by placental ischemia in pregnant rats

Fig. 2

AT1R blockade prevents placental ischemia-induced impairments in CBF autoregulation. a Blood pressure was plotted against % change in CBF for Sham (n = 4), RUPP (n = 7), Sham + losartan (n = 4), and RUPP+losartan (n = 3) groups. *p < 0.05 compared with Sham. #p < 0.05 compared to Sham, Sham+losartan, RUPP+losartan. b Autoregulatory Index was plotted against changes in MAP. Dashed horizontal line (AI = 1) corresponds to the complete loss of autoregulation. *p < 0.05 RUPP vs. Sham group effect. Data represent mean ± SEM. Statistics calculated using three way repeated measures ANOVA

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